atp1b3a ATPase Na+/K+ transporting subunit beta 3a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atp1b3aprovided by ZNC
Official Full Name: ATPase Na+/K+ transporting subunit beta 3aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-990415-167
See related: Ensembl:ENSDARG00000015790 AllianceGenome:ZFIN:ZDB-GENE-990415-167
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb713; atp1b3; nakatpb; wu:fa14a07
Summary: Predicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to act upstream of or within potassium ion transport and sodium ion transport. Predicted to be located in membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Is expressed in several structures, including anterior axial hypoblast; immature eye; mesoderm; nervous system; and neural tube. Orthologous to human ATP1B3 (ATPase Na+/K+ transporting subunit beta 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (16547706..16565688, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (16879116..16897098, complement)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

There are different functional roles for individual Na,K-ATPase genes in zebrafish ear development
Title: Differential expression of Na,K-ATPase alpha and beta subunit genes in the developing zebrafish inner ear.

Submit: New GeneRIF Correction

General gene information

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Markers

atp1b (e-PCR)
- UniSTS:186929

fc48h10 (e-PCR)
- UniSTS:189239

fa14a07.s1 (e-PCR)
- UniSTS:202373

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATPase activator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in intracellular potassium ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular sodium ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in potassium ion import across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within potassium ion transport	IEA Inferred from Electronic Annotation more info
involved_in sodium ion export across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within sodium ion transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of sodium:potassium-exchanging ATPase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of sodium:potassium-exchanging ATPase complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sodium/potassium-transporting ATPase subunit beta-3a

Names: ATPase, Na+/K+ beta 3 polypeptide; ATPase, Na+/K+ beta 3a polypeptide; ATPase, Na+/K+ transporting, beta 3a polypeptide; NA,K-ATPase B subunit; etID309715.2

NP_571296.2

EC 7.2.2.13

XP_068079034.1

EC 7.2.2.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.