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    cpne2 copine II [ Danio rerio (zebrafish) ]

    Gene ID: 565225, updated on 9-Dec-2024

    Summary

    Official Symbol
    cpne2provided by ZNC
    Official Full Name
    copine IIprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7896
    See related
    Ensembl:ENSDARG00000007753 AllianceGenome:ZFIN:ZDB-GENE-030131-7896
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj39e04; wu:fj39e04; si:ch211-122c9.1
    Summary
    Predicted to enable calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion. Predicted to be active in plasma membrane. Orthologous to human CPNE2 (copine 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See cpne2 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (17660373..17703462)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (17671082..17714396)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene cholesteryl ester transfer protein, plasma Neighboring gene NLR family, CARD domain containing 5 Neighboring gene proteasome activator subunit 3 interacting protein 1 Neighboring gene ring finger and SPRY domain containing 1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium-dependent phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium-dependent phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to calcium ion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045075.2NP_001038540.1  copine-2

      Status: PROVISIONAL

      Source sequence(s)
      BX470074, BX470170
      UniProtKB/TrEMBL
      A0A8N7UYA4, Q1LX40
      Related
      ENSDARP00000002576.8, ENSDART00000021213.9
      Conserved Domains (3) summary
      cd04047
      Location:171283
      C2B_Copine; C2 domain second repeat in Copine
      cd04048
      Location:40157
      C2A_Copine; C2 domain first repeat in Copine
      cd01459
      Location:294545
      vWA_copine_like; VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae. ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      17660373..17703462
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005159116.5XP_005159173.1  copine-2 isoform X1

      UniProtKB/TrEMBL
      A0A2R8Q0R6, A0A8M2B629
      Related
      ENSDARP00000146042.1, ENSDART00000186279.1
      Conserved Domains (3) summary
      cd04047
      Location:153265
      C2B_Copine; C2 domain second repeat in Copine
      cd04048
      Location:22139
      C2A_Copine; C2 domain first repeat in Copine
      cd01459
      Location:276527
      vWA_copine_like; VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae. ...