wdr82 WD repeat domain 82 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: wdr82provided by ZNC
Official Full Name: WD repeat domain 82provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-333
See related: Ensembl:ENSDARG00000014083 AllianceGenome:ZFIN:ZDB-GENE-030131-333
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: PTK9L; zgc:55453; zgc:85635; zgc:91817; wu:fb22h06
Summary: Predicted to enable chromatin binding activity. Predicted to be involved in RNA catabolic process and negative regulation of DNA-templated transcription. Predicted to act upstream of or within DNA-templated transcription termination. Predicted to be located in chromosome and nucleus. Predicted to be part of Set1C/COMPASS complex. Orthologous to human WDR82 (WD repeat domain 82). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (41453078..41460616)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (41455542..41463080)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA-templated transcription termination	IEA Inferred from Electronic Annotation more info
involved_in lncRNA catabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of DNA-templated transcription, elongation	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of lncRNA transcription	ISS Inferred from Sequence or Structural Similarity more info
involved_in nuclear RNA surveillance	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of Set1C/COMPASS complex	IBA Inferred from Biological aspect of Ancestor more info
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: WD repeat-containing protein 82

Names: WD repeat domain containing 82; protein word of mouth; wom; word of mouth

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001166268.1 → NP_001159740.1 WD repeat-containing protein 82

See identical proteins and their annotated locations for NP_001159740.1

Status: PROVISIONAL

Source sequence(s)

BC068335

UniProtKB/Swiss-Prot

Q6NV31, Q803V6

Related

ENSDARP00000019685.7, ENSDART00000007353.9

Conserved Domains (3) summary

COG2319
Location:10 → 303

WD40; WD40 repeat [General function prediction only]

cd00200
Location:15 → 300

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:24 → 61

7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

41453078..41460616

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_199551.1: Suppressed sequence

Description

NM_199551.1: This RefSeq was permanently suppressed because it is now thought that the transcript is a read-through overlapping two separated genes, and the read-through protein is not supported.