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    vps29 VPS29 retromer complex component [ Danio rerio (zebrafish) ]

    Gene ID: 573437, updated on 9-Dec-2024

    Summary

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    Official Symbol
    vps29provided by ZNC
    Official Full Name
    VPS29 retromer complex componentprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8764
    See related
    Ensembl:ENSDARG00000069521 AllianceGenome:ZFIN:ZDB-GENE-030131-8764
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb06g05; zgc:56191; zgc:86638; wu:fb06g05
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in endocytic recycling; intracellular protein transport; and retrograde transport, endosome to Golgi. Predicted to act upstream of or within protein transport. Predicted to be located in endosome membrane. Predicted to be part of retromer complex. Predicted to be active in endosome. Orthologous to human VPS29 (VPS29 retromer complex component). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See vps29 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (17005731..17011574)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (16969095..16974938)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene unc-5 netrin receptor Da Neighboring gene aquaporin 3b Neighboring gene family with sequence similarity 216 member A Neighboring gene GPN-loop GTPase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Migratory Neural Crest Cells Phagocytose Dead Cells in the Developing Nervous System. Zhu Y, et al. Cell, 2019 Sep 19. PMID 31495570, Free PMC Article
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC56191, MGC86638

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endocytic recycling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within retrograde transport, endosome to Golgi IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of retromer complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of retromer complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of retromer complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    vacuolar protein sorting-associated protein 29
    Names
    vacuolar protein sorting 29 homolog
    vesicle protein sorting 29
    NP_956331.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200037.2 → NP_956331.1  vacuolar protein sorting-associated protein 29

      See identical proteins and their annotated locations for NP_956331.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045981
      UniProtKB/Swiss-Prot
      Q7ZV68
      Related
      ENSDARP00000092020.3, ENSDART00000101246.4
      Conserved Domains (1) summary
      cd07394
      Location:2 → 179
      MPP_Vps29; Homo sapiens Vps29 and related proteins, metallophosphatase domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      17005731..17011574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7ZV68.1 GenPept UniProtKB/Swiss-Prot:Q7ZV68

    Gene LinkOut

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