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    riox2 ribosomal oxygenase 2 [ Danio rerio (zebrafish) ]

    Gene ID: 393308, updated on 9-Dec-2024

    Summary

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    Official Symbol
    riox2provided by ZNC
    Official Full Name
    ribosomal oxygenase 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1283
    See related
    Ensembl:ENSDARG00000036359 AllianceGenome:ZFIN:ZDB-GENE-040426-1283
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    minal; mina53; zgc:63873
    Summary
    Predicted to enable histone H3K36 demethylase activity and histone H3K4 demethylase activity. Predicted to be located in nucleus. Predicted to be active in nucleolus. Is expressed in immature eye; nervous system; neural plate; segmental plate; and somite. Orthologous to human RIOX2 (ribosomal oxygenase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See riox2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (22461..28202)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (37149..42849)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene TIP41, TOR signaling pathway regulator-like (S. cerevisiae) Neighboring gene crystallin beta-gamma domain containing 3 Neighboring gene SIM bHLH transcription factor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression. Yu SH, et al. Biochim Biophys Acta Gene Regul Mech, 2018 Feb. PMID 29378332, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC63873

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 2-oxoglutarate-dependent dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H3K36 demethylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone H3K4 demethylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal oxygenase 2
    Names
    MYC induced nuclear antigen-like
    NP_956631.1
    XP_021334790.1
    XP_021334791.1
    XP_068079837.1
    XP_068079838.1
    XP_068079839.1
    XP_068079840.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200337.1 → NP_956631.1  ribosomal oxygenase 2

      See identical proteins and their annotated locations for NP_956631.1

      Status: PROVISIONAL

      Source sequence(s)
      BC053125
      UniProtKB/TrEMBL
      Q7T3G6
      Related
      ENSDARP00000025350.7, ENSDART00000022840.8
      Conserved Domains (1) summary
      pfam08007
      Location:70 → 397
      Cupin_4; Cupin superfamily protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      22461..28202
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021479115.2 → XP_021334790.1  ribosomal oxygenase 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9QKJ8
      Conserved Domains (1) summary
      pfam08007
      Location:70 → 380
      Cupin_4; Cupin superfamily protein

    2. XM_021479116.2 → XP_021334791.1  ribosomal oxygenase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M9QGE9
      Conserved Domains (1) summary
      pfam08007
      Location:69 → 379
      Cupin_4; Cupin superfamily protein

    3. XM_068223736.1 → XP_068079837.1  ribosomal oxygenase 2 isoform X1

    4. XM_068223737.1 → XP_068079838.1  ribosomal oxygenase 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9QKJ8

    5. XM_068223738.1 → XP_068079839.1  ribosomal oxygenase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M9QGE9

    6. XM_068223739.1 → XP_068079840.1  ribosomal oxygenase 2 isoform X4

      UniProtKB/TrEMBL
      A0A8M9PTE3
    Nucleotide Protein Strain
    Heading Accession and Version

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