cyp27a1.1 cytochrome P450, family 27, subfamily A, polypeptide 1.1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cyp27a1.1provided by ZNC
Official Full Name: cytochrome P450, family 27, subfamily A, polypeptide 1.1provided by ZNC
Primary source: ZFIN:ZDB-GENE-081104-519
See related: Ensembl:ENSDARG00000033802 AllianceGenome:ZFIN:ZDB-GENE-081104-519
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cyp27a7; si:dkeyp-68f9.9
Summary: Predicted to enable cholesterol 26-hydroxylase activity and vitamin D3 25-hydroxylase activity. Predicted to be involved in calcitriol biosynthetic process from calciol and cholesterol metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (38408991..38419141)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (38599012..38609345)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables cholesterol 26-hydroxylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables heme binding	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info
enables vitamin D3 25-hydroxylase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in calcitriol biosynthetic process from calciol	IBA Inferred from Biological aspect of Ancestor more info
involved_in cholesterol metabolic process	IBA Inferred from Biological aspect of Ancestor more info