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    ints13 integrator complex subunit 13 [ Danio rerio (zebrafish) ]

    Gene ID: 334292, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ints13provided by ZNC
    Official Full Name
    integrator complex subunit 13provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6224
    See related
    Ensembl:ENSDARG00000011764 AllianceGenome:ZFIN:ZDB-GENE-030131-6224
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    asun; fi39e09; zgc:55466; wu:fi39e09
    Summary
    Predicted to be involved in centrosome localization and regulation of mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. Predicted to be part of integrator complex. Orthologous to human INTS13 (integrator complex subunit 13). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See ints13 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (20485494..20499668)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (20765037..20778693)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene calcium channel, voltage-dependent, alpha 2/delta subunit 4a Neighboring gene leucine-rich repeats and transmembrane domains 2a Neighboring gene calcium channel, voltage-dependent, L type, alpha 1C subunit Neighboring gene decapping mRNA 1B Neighboring gene N-acyl phosphatidylethanolamine phospholipase D Neighboring gene sialic acid-binding Ig-like lectin 7 Neighboring gene Ras association domain family member 8b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in centrosome localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of integrator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    integrator complex subunit 13
    Names
    asunder, spermatogenesis regulator homolog (Drosphila)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199883.1 → NP_956177.1  integrator complex subunit 13

      See identical proteins and their annotated locations for NP_956177.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045349
      UniProtKB/TrEMBL
      Q7ZVZ8
      Related
      ENSDARP00000011401.5, ENSDART00000017572.7
      Conserved Domains (1) summary
      pfam10221
      Location:7 → 689
      DUF2151; Cell cycle and development regulator

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      20485494..20499668
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068219529.1 → XP_068075630.1  integrator complex subunit 13 isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z599

    2. XM_017354950.2 → XP_017210439.1  integrator complex subunit 13 isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z599
    Nucleotide Protein Strain
    Heading Accession and Version

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