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    fbxo42 F-box protein 42 [ Danio rerio (zebrafish) ]

    Gene ID: 335459, updated on 27-Dec-2024

    Summary

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    Official Symbol
    fbxo42provided by ZNC
    Official Full Name
    F-box protein 42provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7399
    See related
    AllianceGenome:ZFIN:ZDB-GENE-030131-7399
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:64224; wu:fj14e08
    Summary
    Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXO42 (F-box protein 42). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: suggests misassembly
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See fbxo42 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (191635..225386, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (218606..241718, complement)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene filamin binding LIM protein 1 Neighboring gene solute carrier family 25 member 34 Neighboring gene rootletin-like Neighboring gene olfactory receptor class A-like protein 1 Neighboring gene olfactory receptor class A related 1 Neighboring gene olfactory receptor class A related 2 Neighboring gene zgc:66156 Neighboring gene uncharacterized LOC137488988 Neighboring gene myosin heavy chain, fast skeletal muscle-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin-like ligase-substrate adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    F-box only protein 42

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212739.1 → NP_997904.1  F-box only protein 42

      See identical proteins and their annotated locations for NP_997904.1

      Status: PROVISIONAL

      Source sequence(s)
      BC053311
      UniProtKB/TrEMBL
      Q7T302
      Conserved Domains (3) summary
      sd00038
      Location:88 → 137
      Kelch; KELCH repeat [structural motif]
      pfam12937
      Location:16 → 51
      F-box-like; F-box-like
      pfam13415
      Location:99 → 151
      Kelch_3; Galactose oxidase, central domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      191635..225386 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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