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    arrdc2 arrestin domain containing 2 [ Danio rerio (zebrafish) ]

    Gene ID: 335206, updated on 9-Dec-2024

    Summary

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    Official Symbol
    arrdc2provided by ZNC
    Official Full Name
    arrestin domain containing 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7146
    See related
    Ensembl:ENSDARG00000020761 AllianceGenome:ZFIN:ZDB-GENE-030131-7146
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:85652; wu:fb70a10; wu:fk89c02
    Summary
    Predicted to be involved in protein transport. Predicted to be active in cytoplasm and plasma membrane. Is expressed in basal plate midbrain region; blood vessel; nervous system; neural rod; and pronephric duct. Orthologous to human ARRDC2 (arrestin domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See arrdc2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (13524503..13533782)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (13466845..13476123)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene homer scaffold protein 3b Neighboring gene uncharacterized LOC137496676 Neighboring gene si:dkey-13m1.5 Neighboring gene si:ch211-1a19.2 Neighboring gene secreted immunoglobulin domain 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. On the origins of arrestin and rhodopsin. Alvarez CE. BMC Evol Biol, 2008 Jul 29. PMID 18664266, Free PMC Article
    2. Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells. Giffen KP, et al. Front Neurosci, 2019. PMID 31680844, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    arrestin domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199939.1 → NP_956233.1  arrestin domain-containing protein 2

      See identical proteins and their annotated locations for NP_956233.1

      Status: PROVISIONAL

      Source sequence(s)
      AY423023
      UniProtKB/TrEMBL
      Q6TEM6
      Related
      ENSDARP00000017762.8, ENSDART00000011362.9
      Conserved Domains (2) summary
      smart01017
      Location:183 → 308
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:9 → 159
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      13524503..13533782
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005155942.4 → XP_005155999.1  arrestin domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B1Y2, E9QI61
      Related
      ENSDARP00000113815.1, ENSDART00000139889.3
      Conserved Domains (2) summary
      smart01017
      Location:178 → 303
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:9 → 154
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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