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    c6ast3 six-cysteine containing astacin protease 3 [ Danio rerio (zebrafish) ]

    Gene ID: 541399, updated on 9-Dec-2024

    Summary

    Official Symbol
    c6ast3provided by ZNC
    Official Full Name
    six-cysteine containing astacin protease 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050320-99
    See related
    Ensembl:ENSDARG00000024503 AllianceGenome:ZFIN:ZDB-GENE-050320-99
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:103606
    Summary
    Predicted to enable metalloendopeptidase activity. Predicted to act upstream of or within proteolysis. Orthologous to human ASTL (astacin like metalloendopeptidase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See c6ast3 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (38642114..38644577, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (38370868..38373302, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene C1q and TNF related 4 Neighboring gene six-cysteine containing astacin protease 4 Neighboring gene nephrosin Neighboring gene six-cysteine containing astacin protease 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity  
    enables metal ion binding  
    enables metalloendopeptidase activity  
    enables metalloendopeptidase activity  
    enables metallopeptidase activity  
    enables peptidase activity  
    enables zinc ion binding  

    General protein information

    Preferred Names
    six-cysteine containing astacin protease 3
    NP_001013544.2
    XP_068078391.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013526.2NP_001013544.2  six-cysteine containing astacin protease 3 precursor

      Status: VALIDATED

      Source sequence(s)
      BX957297
      UniProtKB/TrEMBL
      Q5BKW6
      Related
      ENSDARP00000099306.2, ENSDART00000114934.3

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      38642114..38644577 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068222290.1XP_068078391.1  six-cysteine containing astacin protease 3 isoform X1

      UniProtKB/TrEMBL
      Q5BKW6
      Related
      ENSDARP00000148405.1, ENSDART00000182307.1
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