U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    tmco6 transmembrane and coiled-coil domains 6 [ Danio rerio (zebrafish) ]

    Gene ID: 559069, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    tmco6provided by ZNC
    Official Full Name
    transmembrane and coiled-coil domains 6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070410-47
    See related
    Ensembl:ENSDARG00000016336 AllianceGenome:ZFIN:ZDB-GENE-070410-47
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:162240
    Summary
    Predicted to be involved in animal organ development. Predicted to be located in membrane. Orthologous to human TMCO6 (transmembrane and coiled-coil domains 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See tmco6 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (8456887..8472393)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (8150749..8166282)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene si:dkey-160o24.3 Neighboring gene eukaryotic translation initiation factor 1A domain containing Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 4 Neighboring gene vascular endothelial growth factor Ba

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC162240

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    transmembrane and coiled-coil domain-containing protein 6

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001089537.1 → NP_001083006.1  transmembrane and coiled-coil domain-containing protein 6

      See identical proteins and their annotated locations for NP_001083006.1

      Status: PROVISIONAL

      Source sequence(s)
      BC139553
      UniProtKB/TrEMBL
      A0A8M3AZM9, A4QNX0
      Related
      ENSDARP00000018110.7, ENSDART00000007738.8
      Conserved Domains (4) summary
      COG5064
      Location:19 → 504
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00020
      Location:117 → 206
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      sd00043
      Location:145 → 183
      ARM; armadillo repeat [structural motif]
      cl01483
      Location:17 → 123
      Com_YlbF; Control of competence regulator ComK, YlbF/YmcA

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      8456887..8472393
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005157147.5 → XP_005157204.1  transmembrane and coiled-coil domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B391, A0A8M3AZM9
      Conserved Domains (3) summary
      cd00020
      Location:308 → 419
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      sd00043
      Location:304 → 334
      ARM; armadillo repeat [structural motif]
      cl01483
      Location:17 → 123
      Com_YlbF; Control of competence regulator ComK, YlbF/YmcA

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394891.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      85234..100715
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools