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    si:dkey-6i22.5 si:dkey-6i22.5 [ Danio rerio (zebrafish) ]

    Gene ID: 564240, updated on 9-Dec-2024

    Summary

    Official Symbol
    si:dkey-6i22.5provided by ZNC
    Official Full Name
    si:dkey-6i22.5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050506-32
    See related
    Ensembl:ENSDARG00000077822 AllianceGenome:ZFIN:ZDB-GENE-050506-32
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:6898523
    Summary
    Predicted to be involved in chromosome segregation. Predicted to act upstream of or within cell division. Predicted to be located in kinetochore and nucleus. Predicted to be part of MIS12/MIND type complex. Human ortholog(s) of this gene implicated in bladder carcinoma and urinary bladder cancer. Orthologous to human PMF1-BGLAP (PMF1-BGLAP readthrough) and PMF1 (polyamine modulated factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See si:dkey-6i22.5 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (22109241..22113637, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (21811998..21816350, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 43 member 1a Neighboring gene mediator complex subunit 19a Neighboring gene thioredoxin-related transmembrane protein 2a Neighboring gene cyclin G1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of MIS12/MIND type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of MIS12/MIND type complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    polyamine-modulated factor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386276.1NP_001373205.1  polyamine-modulated factor 1

      Status: VALIDATED

      Source sequence(s)
      CU062437
      UniProtKB/TrEMBL
      A0A8M9QKW9, F1Q903
      Related
      ENSDARP00000103590.2, ENSDART00000113752.3
      Conserved Domains (1) summary
      pfam03980
      Location:80178
      Nnf1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      22109241..22113637 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394904.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      291260..295656 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)