reep2 receptor accessory protein 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: reep2provided by ZNC
Official Full Name: receptor accessory protein 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-050706-125
See related: Ensembl:ENSDARG00000031382 AllianceGenome:ZFIN:ZDB-GENE-050706-125
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:110128
Summary: Predicted to enable microtubule binding activity and taste receptor binding activity. Predicted to be involved in endoplasmic reticulum tubular network organization. Predicted to be located in membrane. Predicted to be active in cytoplasmic microtubule; endoplasmic reticulum membrane; and endoplasmic reticulum tubular network. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 72A. Orthologous to human REEP2 (receptor accessory protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (21596716..21618027, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (21299471..21320760, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables taste receptor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in endoplasmic reticulum tubular network organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasmic microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasmic microtubule	ISS Inferred from Sequence or Structural Similarity more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endoplasmic reticulum tubular network	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: receptor expression-enhancing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030227.1 → NP_001025398.1 receptor expression-enhancing protein 2

See identical proteins and their annotated locations for NP_001025398.1

Status: PROVISIONAL

Source sequence(s)

BC098549

UniProtKB/Swiss-Prot

Q4KMI4

Related

ENSDARP00000043161.6, ENSDART00000043162.7

Conserved Domains (1) summary

pfam03134
Location:7 → 94

TB2_DP1_HVA22; TB2/DP1, HVA22 family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007125.7 Reference GRCz11 Primary Assembly

Range

21596716..21618027 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005173132.4 → XP_005173189.1 receptor expression-enhancing protein 2 isoform X1

UniProtKB/TrEMBL

A0A8M2BKF7

Conserved Domains (1) summary

pfam03134
Location:7 → 94

TB2_DP1_HVA22; TB2/DP1, HVA22 family