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    rasal3 RAS protein activator like 3 [ Danio rerio (zebrafish) ]

    Gene ID: 798492, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rasal3provided by ZNC
    Official Full Name
    RAS protein activator like 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-101130-3
    See related
    Ensembl:ENSDARG00000089933 AllianceGenome:ZFIN:ZDB-GENE-101130-3
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable GTPase activator activity. Orthologous to human RASAL3 (RAS protein activator like 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See rasal3 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (8470661..8490125, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (8235122..8254642, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137495918 Neighboring gene prostaglandin E receptor 1a (subtype EP1) Neighboring gene WIZ zinc finger a Neighboring gene peptidoglycan recognition protein 2 Neighboring gene myosin, heavy chain 11a, smooth muscle

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    disabled homolog 2-interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      8470661..8490125 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165747.5 → XP_005165804.1  disabled homolog 2-interacting protein

      UniProtKB/TrEMBL
      A0A8M2BD44, E7FDZ7
      Related
      ENSDARP00000106789.2, ENSDART00000124643.4
      Conserved Domains (4) summary
      cd04013
      Location:374 → 549
      C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
      cd05136
      Location:540 → 862
      RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
      smart00323
      Location:532 → 859
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13262
      Location:256 → 382
      PH_RasSynGAP-like; Synaptic Ras-GTPase activating protein family Pleckstrin homology (PH) domain
    Nucleotide Protein Strain
    Heading Accession and Version

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