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    hdac11 histone deacetylase 11 [ Danio rerio (zebrafish) ]

    Gene ID: 431718, updated on 4-Jan-2025

    Summary

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    Official Symbol
    hdac11provided by ZNC
    Official Full Name
    histone deacetylase 11provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040704-7
    See related
    Ensembl:ENSDARG00000087573 AllianceGenome:ZFIN:ZDB-GENE-040704-7
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:91942
    Summary
    Predicted to enable histone deacetylase activity. Is expressed in telencephalon. Orthologous to human HDAC11 (histone deacetylase 11). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See hdac11 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (27133491..27199498)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (26896058..26950280)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene IQ motif and Sec7 domain ArfGEF 1b Neighboring gene acyl-CoA dehydrogenase family, member 9 Neighboring gene fibulin 2 Neighboring gene wingless-type MMTV integration site family, member 7Aa

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Histone deacetylase 10 structure and molecular function as a polyamine deacetylase. Hai Y, et al. Nat Commun, 2017 May 18. PMID 28516954, Free PMC Article
    2. Histone Deacetylase-Mediated Müller Glia Reprogramming through Her4.1-Lin28a Axis Is Essential for Retina Regeneration in Zebrafish. Mitra S, et al. iScience, 2018 Sep 28. PMID 30267687, Free PMC Article
    3. Identification and expression of mangrove rivulus (Kryptolebias marmoratus) histone deacetylase (HDAC) and lysine acetyltransferase (KAT) genes. Fellous A, et al. Gene, 2019 Apr 5. PMID 30615915
    4. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    5. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables histone deacetylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    histone deacetylase 11
    NP_001002171.1
    XP_021335266.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002171.1 → NP_001002171.1  histone deacetylase 11

      See identical proteins and their annotated locations for NP_001002171.1

      Status: PROVISIONAL

      Source sequence(s)
      BC074052
      UniProtKB/TrEMBL
      Q6GMJ4
      Related
      ENSDARP00000134194.2, ENSDART00000158411.2
      Conserved Domains (1) summary
      cd09993
      Location:46 → 330
      HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      27133491..27199498
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021479591.2 → XP_021335266.1  histone deacetylase 11 isoform X1

      UniProtKB/TrEMBL
      A0A8M9QHL6
      Conserved Domains (1) summary
      cd09993
      Location:46 → 339
      HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11
    Nucleotide Protein
    Heading Accession and Version

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