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    cux1b cut-like homeobox 1b [ Danio rerio (zebrafish) ]

    Gene ID: 445120, updated on 9-Dec-2024

    Summary

    Official Symbol
    cux1bprovided by ZNC
    Official Full Name
    cut-like homeobox 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040801-260
    See related
    Ensembl:ENSDARG00000043134 AllianceGenome:ZFIN:ZDB-GENE-040801-260
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cutl1; zgc:86612; id:ibd1033
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within intra-Golgi vesicle-mediated transport. Predicted to be located in Golgi membrane. Predicted to be active in nucleus. Is expressed in several structures, including adaxial cell; cardiovascular system; immature eye; musculature system; and notochord. Orthologous to human CUX1 (cut like homeobox 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See cux1b in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (2520344..2543832)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (2556772..2580260)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene WD repeat domain 53 Neighboring gene SRP receptor subunit beta Neighboring gene SH2B adaptor protein 2 Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 30b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within intra-Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cut-like homeobox 1b
    Names
    cut-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003514.1NP_001003514.1  cut-like homeobox 1b

      See identical proteins and their annotated locations for NP_001003514.1

      Status: PROVISIONAL

      Source sequence(s)
      BC075748
      UniProtKB/TrEMBL
      Q6DI42
      Related
      ENSDARP00000063328.4, ENSDART00000063329.6
      Conserved Domains (2) summary
      pfam08172
      Location:424638
      CASP_C; CASP C terminal
      cl19219
      Location:117209
      DUF342; Protein of unknown function (DUF342)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      2520344..2543832
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)