bag5 BCL2 associated athanogene 5 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: bag5provided by ZNC
Official Full Name: BCL2 associated athanogene 5provided by ZNC
Primary source: ZFIN:ZDB-GENE-050913-58
See related: Ensembl:ENSDARG00000017316 AllianceGenome:ZFIN:ZDB-GENE-050913-58
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:114117
Summary: Predicted to enable adenyl-nucleotide exchange factor activity and protein-folding chaperone binding activity. Predicted to be involved in negative regulation of protein ubiquitination; protein stabilization; and regulation of inclusion body assembly. Predicted to be active in cytosol; membrane; and nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2F. Orthologous to human BAG5 (BAG cochaperone 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (15757017..15799243, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (15631010..15668250, complement)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fb93a09.x1 (e-PCR)
- UniSTS:203526

G39820 (e-PCR)
- UniSTS:12645

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables adenyl-nucleotide exchange factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-folding chaperone binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein-folding chaperone binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in negative regulation of protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein stabilization	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of inclusion body assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: BAG family molecular chaperone regulator 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.