ap1g1 adaptor related protein complex 1 subunit gamma 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ap1g1provided by ZNC
Official Full Name: adaptor related protein complex 1 subunit gamma 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-3187
See related: Ensembl:ENSDARG00000102394 AllianceGenome:ZFIN:ZDB-GENE-030131-3187
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: adtg; zgc:56079; wu:fc30a11
Summary: Acts upstream of or within several processes, including axis elongation; pectoral fin development; and vasculature development. Predicted to be located in Golgi apparatus; cytoplasmic vesicle; and membrane. Predicted to be part of AP-1 adaptor complex. Is expressed in liver and midbrain hindbrain boundary. Orthologous to human AP1G1 (adaptor related protein complex 1 subunit gamma 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (69304486..69352443, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (68999085..69115145, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Deficiency of AP1 Complex Ap1g1 in Zebrafish Model Led to Perturbation of Neurodevelopment, Female and Male Fertility; New Insight to Understand Adaptinopathies.
Title: Deficiency of AP1 Complex Ap1g1 in Zebrafish Model Led to Perturbation of Neurodevelopment, Female and Male Fertility; New Insight to Understand Adaptinopathies.

Submit: New GeneRIF Correction

General gene information

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Markers

fc30a11.x1 (e-PCR)
- UniSTS:193474

AI721614 (e-PCR)
- UniSTS:206057

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within axis elongation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within axis elongation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within central nervous system development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within central nervous system development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within pectoral fin development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vasculature development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within vasculature development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of AP-1 adaptor complex	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of membrane coat	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: AP-1 complex subunit gamma-1

Names: adaptor protein complex AP-1, gamma 1 subunit; adaptor-related protein complex 1, gamma 1 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199682.1 → NP_955976.1 AP-1 complex subunit gamma-1

See identical proteins and their annotated locations for NP_955976.1

Status: PROVISIONAL

Source sequence(s)

BC047823

UniProtKB/TrEMBL

A0A8M6YZX7, Q7ZUU8

Related

ENSDARP00000139530.1, ENSDART00000170714.3

Conserved Domains (3) summary

smart00809
Location:706 → 814

Alpha_adaptinC2; Adaptin C-terminal domain

pfam01602
Location:23 → 573

Adaptin_N; Adaptin N terminal region

sd00044
Location:142 → 163

HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007118.7 Reference GRCz11 Primary Assembly

Range

69304486..69352443 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068222169.1 → XP_068078270.1 AP-1 complex subunit gamma-1 isoform X2

UniProtKB/TrEMBL

A0A8M6Z1G8
XM_068222168.1 → XP_068078269.1 AP-1 complex subunit gamma-1 isoform X1

UniProtKB/TrEMBL

A0A8M6YZX7