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    nptna neuroplastin a [ Danio rerio (zebrafish) ]

    Gene ID: 368305, updated on 4-Jan-2025

    Summary

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    Official Symbol
    nptnaprovided by ZNC
    Official Full Name
    neuroplastin aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030804-7
    See related
    Ensembl:ENSDARG00000103002 AllianceGenome:ZFIN:ZDB-GENE-030804-7
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb578; wu:fj19g07; zgc:162565
    Summary
    Acts upstream of or within response to steroid hormone. Predicted to be located in membrane. Is expressed in nervous system; neural tube; ovary; and trigeminal placode. Orthologous to human NPTN (neuroplastin). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See nptna in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (29318924..29363429, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (28875921..28920255, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137489403 Neighboring gene pyruvate kinase M1/2b Neighboring gene hyperpolarization activated cyclic nucleotide-gated potassium channel 4l Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide A5 Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide A4 Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide A3 Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide A2 Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Fine selection of up-regulated genes during ovulation by in vivo induction of oocyte maturation and ovulation in zebrafish. Klangnurak W, et al. Zoological Lett, 2017. PMID 28265462, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within response to steroid hormone IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    neuroplastin a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001160156.2 → NP_001153628.1  neuroplastin a precursor

      See identical proteins and their annotated locations for NP_001153628.1

      Status: VALIDATED

      Source sequence(s)
      CABZ01033722, CABZ01054603, CABZ01115946, CABZ01115947, CU469568, CU855691
      UniProtKB/TrEMBL
      A0A0R4IT67, A4IGC1, A4JYL1
      Related
      ENSDARP00000137543.1, ENSDART00000166889.3
      Conserved Domains (2) summary
      smart00410
      Location:128 → 212
      IG_like; Immunoglobulin like
      cl11960
      Location:116 → 212
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      29318924..29363429 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068217333.1 → XP_068073434.1  neuroplastin a isoform X3

    2. XM_068217332.1 → XP_068073433.1  neuroplastin a isoform X2

    3. XM_068217331.1 → XP_068073432.1  neuroplastin a isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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