U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Prss16 serine protease 16 (thymus) [ Mus musculus (house mouse) ]

    Gene ID: 54373, updated on 9-Dec-2024

    Summary

    Official Symbol
    Prss16provided by MGI
    Official Full Name
    serine protease 16 (thymus)provided by MGI
    Primary source
    MGI:MGI:1859181
    See related
    Ensembl:ENSMUSG00000006179 AllianceGenome:MGI:1859181
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TSSP
    Summary
    Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Located in endosome and lysosome. Is expressed in epididymis; prostate gland; testis; and thymus. Orthologous to human PRSS16 (serine protease 16). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward thymus adult (RPKM 217.8) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Prss16 in Genome Data Viewer
    Location:
    13 A3.1; 13 8.12 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (22186346..22193911, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (22002176..22009741, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA serine 8 (anticodon GCT) Neighboring gene nuclear encoded tRNA glutamine 1 (anticodon CTG) Neighboring gene STARR-positive B cell enhancer mm9_chr13:22107605-22107906 Neighboring gene nuclear encoded tRNA valine 3 (anticodon AAC) Neighboring gene STARR-positive B cell enhancer ABC_E7211 Neighboring gene nuclear encoded tRNA arginine 1 (anticodon ACG)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (4)  1 citation

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables dipeptidyl-peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables serine-type exopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in lysosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    thymus-specific serine protease
    Names
    protease, serine 16 (thymus)
    serine protease 16

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019429.2NP_062302.1  thymus-specific serine protease precursor

      Status: PROVISIONAL

      Source sequence(s)
      AL590614
      Consensus CDS
      CCDS26303.1
      UniProtKB/Swiss-Prot
      Q9QXE5
      UniProtKB/TrEMBL
      Q5SZ30
      Related
      ENSMUSP00000006341.3, ENSMUST00000006341.4
      Conserved Domains (1) summary
      pfam05577
      Location:63493
      Peptidase_S28; Serine carboxypeptidase S28

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      22186346..22193911 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)