Samd1 sterile alpha motif domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Samd1provided by RGD
Full Name: sterile alpha motif domain containing 1provided by RGD
Primary source: RGD:7529921
See related: EnsemblRapid:ENSRNOG00000065861 AllianceGenome:RGD:7529921
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1305094
Summary: Predicted to enable chromatin binding activity and low-density lipoprotein particle binding activity. Predicted to be involved in several processes, including lipoprotein lipid oxidation; protein homooligomerization; and regulation of gene expression. Predicted to be active in extracellular space and nucleus. Orthologous to human SAMD1 (sterile alpha motif domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 109.3), Heart (RPKM 60.6) and 9 other tissues See more
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (41055898..41059243, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (24151136..24154475, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (25119560..25122781)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables chromatin binding	ISO Inferred from Sequence Orthology more info
enables low-density lipoprotein particle binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in chromatin organization	IEA Inferred from Electronic Annotation more info
involved_in foam cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in lipoprotein lipid oxidation	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of transcription initiation-coupled chromatin remodeling	ISO Inferred from Sequence Orthology more info
involved_in protein homooligomerization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in extracellular space	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	ISO Inferred from Sequence Orthology more info

Preferred Names: sterile alpha motif domain containing 1; sterile alpha motif domain-containing protein 1

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_039098144.2 → XP_038954072.1 sterile alpha motif domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A8I6AKG2

Related

ENSRNOP00000093467.1, ENSRNOT00000103556.2

Conserved Domains (1) summary

cd09583
Location:440 → 508

SAM_Atherin-like; SAM domain of Atherin/Atherin-like subfamily
XM_039098145.2 → XP_038954073.1 sterile alpha motif domain-containing protein 1 isoform X2