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    Lt1 lurcher transcript 1 [ Mus musculus (house mouse) ]

    Gene ID: 16991, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lt1provided by MGI
    Official Full Name
    lurcher transcript 1provided by MGI
    Primary source
    MGI:MGI:1100855
    See related
    AllianceGenome:MGI:1100855
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Acts upstream of or within cerebellar Purkinje cell layer development and locomotory behavior. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Lt1 in Genome Data Viewer
    Location:
    6 C1; 6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (64873937..64876425)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (64896953..64899441)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene atonal bHLH transcription factor 1 Neighboring gene STARR-seq mESC enhancer starr_16115 Neighboring gene STARR-seq mESC enhancer starr_16116 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_16119 Neighboring gene STARR-seq mESC enhancer starr_16124 Neighboring gene sorting nexin 10 pseudogene Neighboring gene STARR-seq mESC enhancer starr_16125 Neighboring gene STARR-seq mESC enhancer starr_16130 Neighboring gene SNF2 related chromatin remodeling ATPase with DExD box 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A relationship between cerebellar Purkinje cells and spatial working memory demonstrated in a lurcher/chimera mouse model system. Martin LA, et al. Genes Brain Behav, 2004 Jun. PMID 15140011
    2. Treadmill performance of mice with cerebellar lesions: 2. Lurcher mutant mice. Le Marec N, et al. Neurobiol Learn Mem, 2000 May. PMID 10775492
    3. The effect of 3-acetylpyridine on inferior olivary neuron degeneration in Lurcher mutant and wild-type mice. Caddy KW, et al. Eur J Pharmacol, 1997 Jul 9. PMID 9253946
    4. An approximately 1.2-Mb bacterial artificial chromosome contig refines the genetic and physical maps of the lurcher locus on mouse chromosome 6. De Jager PL, et al. Genome Res, 1997 Jul. PMID 9253602, Free PMC Article
    5. A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice. Poltorak A, et al. J Immunol, 2001 Aug 15. PMID 11489994

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Other Names

    • regulation of nuclear pre-mRNA domain containing 1A pseudogene

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within cerebellar Purkinje cell layer development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within locomotory behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_023459.1 

      Range
      101..2589
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      64873937..64876425
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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