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    Fsd2 fibronectin type III and SPRY domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 244091, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fsd2provided by MGI
    Official Full Name
    fibronectin type III and SPRY domain containing 2provided by MGI
    Primary source
    MGI:MGI:2444310
    See related
    Ensembl:ENSMUSG00000038663 AllianceGenome:MGI:2444310
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Spryd1; 9830160G03Rik
    Summary
    Predicted to be located in nucleus; perinuclear region of cytoplasm; and sarcoplasmic reticulum. Is expressed in hindlimb long bone and tarsus. Orthologous to human FSD2 (fibronectin type III and SPRY domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in heart adult (RPKM 56.7), mammary gland adult (RPKM 6.8) and 2 other tissues See more
    Orthologs
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    Genomic context

    See Fsd2 in Genome Data Viewer
    Location:
    7 D3; 7 45.71 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (81184102..81216729, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (81534354..81566981, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 45991 Neighboring gene RIKEN cDNA 2900076A07 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:88668387-88668540 Neighboring gene microRNA 1839 Neighboring gene STARR-seq mESC enhancer starr_19369 Neighboring gene STARR-positive B cell enhancer mm9_chr7:88715937-88716238 Neighboring gene WAS protein homolog associated with actin, golgi membranes and microtubules Neighboring gene homer scaffolding protein 2 Neighboring gene microRNA 12203

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in perinuclear region of cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in sarcoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    fibronectin type III and SPRY domain-containing protein 2
    Names
    SPRY domain containing 1
    SPRY domain-containing protein 1
    minispryn

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172904.2NP_766492.2  fibronectin type III and SPRY domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AK028142, AK036674, BY067791
      Consensus CDS
      CCDS80743.1
      UniProtKB/Swiss-Prot
      A0A140T8J1, E9QMV0, Q8BZ52
      Related
      ENSMUSP00000047775.7, ENSMUST00000042318.6
      Conserved Domains (4) summary
      smart00060
      Location:339424
      FN3; Fibronectin type 3 domain
      cd00063
      Location:436528
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl02614
      Location:532707
      SPRY; SPRY domain
      cl25602
      Location:174290
      DUF3552; Domain of unknown function (DUF3552)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      81184102..81216729 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)