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    Spata32 spermatogenesis associated 32 [ Mus musculus (house mouse) ]

    Gene ID: 328019, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Spata32provided by MGI
    Official Full Name
    spermatogenesis associated 32provided by MGI
    Primary source
    MGI:MGI:3045340
    See related
    Ensembl:ENSMUSG00000044787 AllianceGenome:MGI:3045340
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    VAD1.2; 4933400C05Rik
    Summary
    Predicted to enable actin binding activity. Predicted to be involved in spermatogenesis. Predicted to be active in perinuclear region of cytoplasm. Is expressed in brain; embryo; heart; spermatid; and testis. Orthologous to human SPATA32 (spermatogenesis associated 32). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 52.4) See more
    Orthologs
    human all
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    Genomic context

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    See Spata32 in Genome Data Viewer
    Location:
    11 E1; 11 66.77 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (103098953..103109258, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (103208127..103218432, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10717 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:103036322-103036635 Neighboring gene predicted gene, 51919 Neighboring gene uncharacterized LOC118567870 Neighboring gene formin-like 1 Neighboring gene EF-hand calcium binding domain 15 Neighboring gene predicted gene, 51920 Neighboring gene mitogen-activated protein kinase kinase kinase 14 Neighboring gene predicted gene, 34823 Neighboring gene STARR-positive B cell enhancer ABC_E10718 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:103128947-103129269 Neighboring gene STARR-seq mESC enhancer starr_30841 Neighboring gene STARR-seq mESC enhancer starr_30842 Neighboring gene STARR-positive B cell enhancer ABC_E3026 Neighboring gene Rho GTPase activating protein 27 Neighboring gene Rho GTPase activating protein 27, opposite strand 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Characterization of an acrosome protein VAD1.2/AEP2 which is differentially expressed in spermatogenesis. Lee KF, et al. Mol Hum Reprod, 2008 Aug. PMID 18621766
    2. Identification of novel genes expressed during spermatogenesis in stage-synchronized rat testes by differential display. Luk JM, et al. Biochem Biophys Res Commun, 2003 Aug 8. PMID 12878178
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Identification and expression analysis of the rat VAD1.2 ortholog.
      Title: Identification of novel genes expressed during spermatogenesis in stage-synchronized rat testes by differential display.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables actin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in spermatogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in perinuclear region of cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    spermatogenesis-associated protein 32
    Names
    acrosome expressed protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177801.3 → NP_808469.1  spermatogenesis-associated protein 32

      See identical proteins and their annotated locations for NP_808469.1

      Status: PROVISIONAL

      Source sequence(s)
      AK077068
      Consensus CDS
      CCDS25515.1
      UniProtKB/Swiss-Prot
      Q8C5V0
      Related
      ENSMUSP00000099365.2, ENSMUST00000103076.2
      Conserved Domains (1) summary
      pfam15310
      Location:106 → 329
      VAD1-2; Vitamin A-deficiency (VAD) rat model signalling

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      103098953..103109258 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156780.1 → XP_036012673.1  spermatogenesis-associated protein 32 isoform X2

      Conserved Domains (1) summary
      pfam15310
      Location:36 → 259
      VAD1-2; Vitamin A-deficiency (VAD) rat model signalling

    2. XM_036156779.1 → XP_036012672.1  spermatogenesis-associated protein 32 isoform X2

      Conserved Domains (1) summary
      pfam15310
      Location:36 → 259
      VAD1-2; Vitamin A-deficiency (VAD) rat model signalling

    3. XM_006533582.5 → XP_006533645.1  spermatogenesis-associated protein 32 isoform X1

      Conserved Domains (1) summary
      pfam15310
      Location:118 → 341
      VAD1-2; Vitamin A-deficiency (VAD) rat model signalling
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C5V0.1 GenPept UniProtKB/Swiss-Prot:Q8C5V0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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