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    Fyttd1 forty-two-three domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 69823, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fyttd1provided by MGI
    Official Full Name
    forty-two-three domain containing 1provided by MGI
    Primary source
    MGI:MGI:1917955
    See related
    Ensembl:ENSMUSG00000022800 AllianceGenome:MGI:1917955
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010005M05Rik; 3830411L18Rik; 3830421F13Rik; 4933423A17Rik
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleoplasm. Predicted to be active in nuclear speck. Is expressed in several structures, including genitourinary system; nasal epithelium; palatal shelf mesenchyme; submandibular gland primordium epithelium; and vibrissa epidermal component. Orthologous to human FYTTD1 (forty-two-three domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in placenta adult (RPKM 15.3), CNS E18 (RPKM 12.6) and 23 other tissues See more
    Orthologs
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    Genomic context

    See Fyttd1 in Genome Data Viewer
    Location:
    16 23.43 cM; 16 B3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (32697762..32729333)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (32877581..32908963)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene mucin 4 Neighboring gene STARR-seq mESC enhancer starr_40675 Neighboring gene mucin 20 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:32813070-32813253 Neighboring gene STARR-seq mESC enhancer starr_40677 Neighboring gene STARR-seq mESC enhancer starr_40678 Neighboring gene somatomedin B domain containing 1 Neighboring gene RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein Neighboring gene VISTA enhancer mm1352 Neighboring gene STARR-positive B cell enhancer mm9_chr16:32877901-32878201 Neighboring gene STARR-positive B cell enhancer ABC_E9930 Neighboring gene STARR-positive B cell enhancer ABC_E8627 Neighboring gene STARR-positive B cell enhancer ABC_E4167 Neighboring gene leucine-rich repeats and calponin homology (CH) domain containing 3 Neighboring gene predicted gene 6611 Neighboring gene nuclear encoded rRNA 5S 33

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mRNA binding  
    enables mRNA binding  
    enables mRNA binding  
    Process Evidence Code Pubs
    involved_in mRNA export from nucleus  
    involved_in mRNA export from nucleus  
    involved_in mRNA export from nucleus  
    Component Evidence Code Pubs
    is_active_in nuclear speck  
    located_in nuclear speck  
    located_in nuclear speck  
    located_in nucleoplasm  
    located_in nucleoplasm  

    General protein information

    Preferred Names
    UAP56-interacting factor
    Names
    forty-two-three domain-containing protein 1
    protein 40-2-3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159349.1NP_001152821.1  UAP56-interacting factor isoform 2

      See identical proteins and their annotated locations for NP_001152821.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of a coding exon and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AC139244, AK139638, BY060615
      Consensus CDS
      CCDS49833.1
      UniProtKB/Swiss-Prot
      Q91Z49
      Related
      ENSMUSP00000131446.2, ENSMUST00000171325.9
      Conserved Domains (1) summary
      pfam07078
      Location:20283
      FYTT; Forty-two-three protein
    2. NM_001356387.1NP_001343316.1  UAP56-interacting factor isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC139244
      Conserved Domains (1) summary
      pfam07078
      Location:20292
      FYTT; Forty-two-three protein
    3. NM_027226.4NP_081502.2  UAP56-interacting factor isoform 1

      See identical proteins and their annotated locations for NP_081502.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC139244, AK170511, BY060615
      Consensus CDS
      CCDS28125.1
      UniProtKB/Swiss-Prot
      Q3TJ68, Q3UT89, Q8BVM8, Q8K361, Q91Z49, Q921B0, Q9D6A8
      Related
      ENSMUSP00000023489.5, ENSMUST00000023489.11
      Conserved Domains (1) summary
      pfam07078
      Location:20317
      FYTT; Forty-two-three protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      32697762..32729333
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522522.4XP_006522585.1  UAP56-interacting factor isoform X1

      See identical proteins and their annotated locations for XP_006522585.1

      Conserved Domains (1) summary
      pfam07078
      Location:1251
      FYTT; Forty-two-three protein
    2. XM_006522523.5XP_006522586.1  UAP56-interacting factor isoform X2

      Conserved Domains (1) summary
      pfam07078
      Location:20218
      FYTT; Forty-two-three protein
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