Treh trehalase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Trehprovided by RGD
Official Full Name: trehalaseprovided by RGD
Primary source: RGD:61831
See related: EnsemblRapid:ENSRNOG00000052010 AllianceGenome:RGD:61831
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable alpha,alpha-trehalase activity. Involved in animal organ morphogenesis. Orthologous to human TREH (trehalase). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 111.6), Brain (RPKM 44.1) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q22

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (53886946..53901113)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (44990182..45003881)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (48983802..48998072)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

BI278154 (e-PCR)
- UniSTS:244248

AU041016 (e-PCR)
- UniSTS:159867

Treh (e-PCR), detects polymorphism
- UniSTS:226180

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables alpha,alpha-trehalase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alpha,alpha-trehalase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in animal organ morphogenesis	IDA Inferred from Direct Assay more info	PubMed
involved_in trehalose catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in trehalose catabolic process	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: trehalase

Names: trehalase (brush-border membrane glycoprotein)

NP_001129613.1

EC 3.2.1.28

XP_017451374.2

EC 3.2.1.28

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.