Fam83e family with sequence similarity 83, member E [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Fam83eprovided by MGI
Official Full Name: family with sequence similarity 83, member Eprovided by MGI
Primary source: MGI:MGI:1921063
See related: Ensembl:ENSMUSG00000054161 AllianceGenome:MGI:1921063
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 4930403C10Rik
Summary: Predicted to enable protein kinase binding activity. Predicted to be involved in signal transduction. Orthologous to human FAM83E (family with sequence similarity 83 member E). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in colon adult (RPKM 185.7), stomach adult (RPKM 49.2) and 4 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 B3; 7 29.46 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (45370595..45379179)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (45721171..45729755)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein kinase binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein kinase binding	IEA Inferred from Electronic Annotation more info
enables protein kinase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in signal transduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: protein FAM83E

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033170.4 → NP_001028342.2 protein FAM83E

See identical proteins and their annotated locations for NP_001028342.2

Status: VALIDATED

Source sequence(s)

AC167242

Consensus CDS

CCDS39959.2

UniProtKB/Swiss-Prot

B9EIA0, Q3UN25, Q80XS7

Related

ENSMUSP00000114397.3, ENSMUST00000129507.5

Conserved Domains (2) summary

pfam07894
Location:21 → 292

DUF1669; Protein of unknown function (DUF1669)

pfam13091
Location:151 → 284

PLDc_2; PLD-like domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

45370595..45379179

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006541224.3 → XP_006541287.1 protein FAM83E isoform X1

Conserved Domains (1) summary

cl15239
Location:19 → 229

PLDc_SF; Catalytic domain of phospholipase D superfamily proteins