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    Wdr25 WD repeat domain 25 [ Mus musculus (house mouse) ]

    Gene ID: 212198, updated on 9-Dec-2024

    Summary

    Official Symbol
    Wdr25provided by MGI
    Official Full Name
    WD repeat domain 25provided by MGI
    Primary source
    MGI:MGI:3045255
    See related
    Ensembl:ENSMUSG00000040877 AllianceGenome:MGI:3045255
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B930090D16Rik
    Summary
    Orthologous to human WDR25 (WD repeat domain 25). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 3.5), testis adult (RPKM 1.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Wdr25 in Genome Data Viewer
    Location:
    12 F1; 12 59.7 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (108860155..108994380)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (108894152..109028454)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 25, member 47 Neighboring gene predicted gene, 22079 Neighboring gene tryptophanyl-tRNA synthetase1 Neighboring gene STARR-positive B cell enhancer ABC_E5353 Neighboring gene STARR-seq mESC enhancer starr_33252 Neighboring gene STARR-seq mESC enhancer starr_33253 Neighboring gene STARR-seq mESC enhancer starr_33254 Neighboring gene peptidyl prolyl isomerase H pseudogene Neighboring gene STARR-seq mESC enhancer starr_33255 Neighboring gene brain-enriched guanylate kinase-associated Neighboring gene predicted gene, 52002 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:110295982-110296239 Neighboring gene STARR-positive B cell enhancer mm9_chr12:110312387-110312688 Neighboring gene STARR-positive B cell enhancer mm9_chr12:110313106-110313407 Neighboring gene macrophage migration inhibitory factor, pseudogene 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (6) 

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in cellular_component  

    General protein information

    Preferred Names
    WD repeat-containing protein 25

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177602.3NP_808270.2  WD repeat-containing protein 25

      See identical proteins and their annotated locations for NP_808270.2

      Status: VALIDATED

      Source sequence(s)
      AC122811, AC140111
      Consensus CDS
      CCDS49172.1
      UniProtKB/Swiss-Prot
      E9Q349, Q8C4T7
      Related
      ENSMUSP00000129855.2, ENSMUST00000167816.8
      Conserved Domains (2) summary
      cd00200
      Location:230534
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:242281
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      108860155..108994380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515661.4XP_006515724.1  WD repeat-containing protein 25 isoform X2

      Conserved Domains (2) summary
      sd00039
      Location:240280
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:230358
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    2. XM_011244056.4XP_011242358.1  WD repeat-containing protein 25 isoform X4

      Conserved Domains (2) summary
      sd00039
      Location:240280
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:230360
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    3. XM_006515660.5XP_006515723.1  WD repeat-containing protein 25 isoform X1

      See identical proteins and their annotated locations for XP_006515723.1

      UniProtKB/Swiss-Prot
      E9Q349, Q8C4T7
      Conserved Domains (2) summary
      cd00200
      Location:230534
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:242281
      7WD40; WD40 repeat [structural motif]
    4. XM_011244054.4XP_011242356.1  WD repeat-containing protein 25 isoform X1

      See identical proteins and their annotated locations for XP_011242356.1

      UniProtKB/Swiss-Prot
      E9Q349, Q8C4T7
      Conserved Domains (2) summary
      cd00200
      Location:230534
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:242281
      7WD40; WD40 repeat [structural motif]
    5. XM_006515657.4XP_006515720.1  WD repeat-containing protein 25 isoform X1

      See identical proteins and their annotated locations for XP_006515720.1

      UniProtKB/Swiss-Prot
      E9Q349, Q8C4T7
      Conserved Domains (2) summary
      cd00200
      Location:230534
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:242281
      7WD40; WD40 repeat [structural motif]
    6. XM_006515662.4XP_006515725.1  WD repeat-containing protein 25 isoform X3

      Conserved Domains (2) summary
      sd00039
      Location:241282
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:228441
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    7. XM_011244057.4XP_011242359.1  WD repeat-containing protein 25 isoform X5

      Conserved Domains (2) summary
      sd00039
      Location:240280
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:230349
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    8. XM_011244055.3XP_011242357.1  WD repeat-containing protein 25 isoform X1

      See identical proteins and their annotated locations for XP_011242357.1

      UniProtKB/Swiss-Prot
      E9Q349, Q8C4T7
      Related
      ENSMUSP00000035553.8, ENSMUST00000047115.9
      Conserved Domains (2) summary
      cd00200
      Location:230534
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:242281
      7WD40; WD40 repeat [structural motif]
    9. XM_006515658.4XP_006515721.1  WD repeat-containing protein 25 isoform X1

      See identical proteins and their annotated locations for XP_006515721.1

      UniProtKB/Swiss-Prot
      E9Q349, Q8C4T7
      Conserved Domains (2) summary
      cd00200
      Location:230534
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:242281
      7WD40; WD40 repeat [structural motif]

    RNA

    1. XR_003950025.2 RNA Sequence

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