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    Esf1 ESF1 nucleolar pre-rRNA processing protein homolog [ Mus musculus (house mouse) ]

    Gene ID: 66580, updated on 9-Dec-2024

    Summary

    Official Symbol
    Esf1provided by MGI
    Official Full Name
    ESF1 nucleolar pre-rRNA processing protein homologprovided by MGI
    Primary source
    MGI:MGI:1913830
    See related
    Ensembl:ENSMUSG00000045624 AllianceGenome:MGI:1913830
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ABTAP; 2610101J03Rik
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus and nucleoplasm. Is expressed in dorsal root ganglion and spinal cord. Orthologous to human ESF1 (ESF1 nucleolar pre-rRNA processing protein homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E11.5 (RPKM 9.1), placenta adult (RPKM 4.4) and 11 other tissues See more
    Orthologs
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    Genomic context

    See Esf1 in Genome Data Viewer
    Location:
    2 F3; 2 69.2 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (139961800..140012498, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (140119881..140170558, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_05838 Neighboring gene STARR-seq mESC enhancer starr_05839 Neighboring gene taspase, threonine aspartase 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:139750776-139750959 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:139760469-139760763 Neighboring gene STARR-positive B cell enhancer mm9_chr2:139792158-139792459 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:139867947-139868134 Neighboring gene STARR-positive B cell enhancer ABC_E4503 Neighboring gene STARR-seq mESC enhancer starr_05842 Neighboring gene ribosomal protein S19, pseudogene 7 Neighboring gene STARR-positive B cell enhancer ABC_E4504 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:139996213-139996396 Neighboring gene STARR-seq mESC enhancer starr_05846 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 5 Neighboring gene predicted gene, 52594 Neighboring gene sel-1 suppressor of lin-12-like 2 (C. elegans) Neighboring gene STARR-seq mESC enhancer starr_05847

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding  
    Process Evidence Code Pubs
    involved_in rRNA processing  
    involved_in rRNA processing  
    Component Evidence Code Pubs
    located_in nucleolus  
    located_in nucleoplasm  

    General protein information

    Preferred Names
    ESF1 homolog
    Names
    ABT1-associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081090.2NP_001074559.1  ESF1 homolog

      See identical proteins and their annotated locations for NP_001074559.1

      Status: VALIDATED

      Source sequence(s)
      AL844528, AL929001, BX294004
      Consensus CDS
      CCDS38250.1
      UniProtKB/Swiss-Prot
      Q3V1V3
      UniProtKB/TrEMBL
      A2APY6, B2RXU2
      Related
      ENSMUSP00000036523.8, ENSMUST00000046030.8
      Conserved Domains (1) summary
      COG5638
      Location:295798
      COG5638; Uncharacterized conserved protein [Function unknown]

    RNA

    1. NR_197784.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL844528, AL929001, BX294004

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      139961800..140012498 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500011.5XP_006500074.1  ESF1 homolog isoform X1

      See identical proteins and their annotated locations for XP_006500074.1

      UniProtKB/Swiss-Prot
      Q3V1V3
      UniProtKB/TrEMBL
      A2APY6, B2RXU2
      Conserved Domains (1) summary
      COG5638
      Location:295798
      COG5638; Uncharacterized conserved protein [Function unknown]
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