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    MES4 methyl esterase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816890, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MES4
    Official Full Name
    methyl esterase 4
    Primary source
    TAIR:AT2G23580
    Locus tag
    AT2G23580
    See related
    Araport:AT2G23580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ABE4; ALPHA/BETA FOLD HYDROLASE/ESTERASE 4; ARABIDOPSIS THALIANA METHYL ESTERASE 4; ATMES4; F26B6.23; F26B6_23; methyl esterase 4
    Summary
    Encodes a protein shown to have carboxylesterase activity and methyl salicylate esterase activity in vitro. This protein does not act on methyl IAA, methyl JA, MeGA4, or MEGA9 in vitro.
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    Genomic context

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    See MES4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (10033043..10034327, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene methyl esterase 7 Neighboring gene methyl esterase 19 Neighboring gene methyl esterase 8 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of likely orthologs of tobacco salicylic acid-binding protein 2 and their role in systemic acquired resistance in Arabidopsis thaliana. Vlot AC, et al. Plant J, 2008 Nov. PMID 18643994
    2. Inactive methyl indole-3-acetic acid ester can be hydrolyzed and activated by several esterases belonging to the AtMES esterase family of Arabidopsis. Yang Y, et al. Plant Physiol, 2008 Jul. PMID 18467465, Free PMC Article
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001202655.1
    NM_127922.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hydrolase activity, acting on ester bonds IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables methyl salicylate esterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within salicylic acid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    methyl esterase 4
    NP_001189584.1
    • methyl esterase 4 (MES4); FUNCTIONS IN: hydrolase activity, hydrolase activity, acting on ester bonds, methyl salicylate esterase activity; INVOLVED IN: salicylic acid metabolic process; CONTAINS InterPro DOMAIN/s: Alpha/beta hydrolase fold-1 (InterPro:IPR000073); BEST Arabidopsis thaliana protein match is: methyl esterase 7 (TAIR:AT2G23560.1).
    NP_179939.1
    • methyl esterase 4 (MES4); CONTAINS InterPro DOMAIN/s: Alpha/beta hydrolase fold-1 (InterPro:IPR000073); BEST Arabidopsis thaliana protein match is: methyl esterase 6 (TAIR:AT2G23550.1); Has 1450 Blast hits to 1448 proteins in 324 species: Archae - 0; Bacteria - 694; Metazoa - 0; Fungi - 30; Plants - 611; Viruses - 0; Other Eukaryotes - 115 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      10033043..10034327 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202655.1 → NP_001189584.1  methyl esterase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189584.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4IMK6
      Conserved Domains (1) summary
      cl21494
      Location:9 → 170
      Abhydrolase; alpha/beta hydrolases

    2. NM_127922.3 → NP_179939.1  methyl esterase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179939.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80474
      UniProtKB/TrEMBL
      A0A178VWI8, A0A5S9X0X2
      Conserved Domains (1) summary
      PLN02211
      Location:2 → 259
      PLN02211; methyl indole-3-acetate methyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80474.1

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