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    Neutral/alkaline non-lysosomal ceramidase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818379, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Neutral/alkaline non-lysosomal ceramidase
    Primary source
    TAIR:AT2G38010
    Locus tag
    AT2G38010
    See related
    Araport:AT2G38010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T8P21.8; T8P21_8
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    8
    Sequence:
    Chromosome: 2; NC_003071.7 (15906555..15909931)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene O-fucosyltransferase family protein Neighboring gene ribosome biogenesis regulatory protein (RRS1) family protein Neighboring gene chaperone protein dnaJ-like protein Neighboring gene vacuoleless1 (VCL1) Neighboring gene Cysteine proteinases superfamily protein Neighboring gene tRNA-Glu

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis ceramidase AtACER functions in disease resistance and salt tolerance. Wu JX, et al. Plant J, 2015 Mar. PMID 25619405
    2. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    3. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001336684.1
    NM_129358.3
    NM_201899.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables N-acylsphingosine amidohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ceramide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    Neutral/alkaline non-lysosomal ceramidase
    NP_181337.2
    • Neutral/alkaline non-lysosomal ceramidase; FUNCTIONS IN: ceramidase activity; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Neutral/alkaline nonlysosomal ceramidase (InterPro:IPR006823); BEST Arabidopsis thaliana protein match is: Neutral/alkaline non-lysosomal ceramidase (TAIR:AT1G07380.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_973628.1
    • Neutral/alkaline non-lysosomal ceramidase; FUNCTIONS IN: ceramidase activity; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Neutral/alkaline nonlysosomal ceramidase (InterPro:IPR006823); BEST Arabidopsis thaliana protein match is: Neutral/alkaline non-lysosomal ceramidase (TAIR:AT1G07380.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      15906555..15909931
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_201899.2 → NP_973628.1  Neutral/alkaline non-lysosomal ceramidase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973628.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q304B9
      Conserved Domains (3) summary
      PTZ00487
      Location:26 → 773
      PTZ00487; ceramidase; Provisional
      pfam04734
      Location:26 → 626
      Ceramidase_alk; Neutral/alkaline non-lysosomal ceramidase, N-terminal
      pfam17048
      Location:628 → 775
      Ceramidse_alk_C; Neutral/alkaline non-lysosomal ceramidase, C-terminal

    2. NM_001336684.1 → NP_001324325.1  Neutral/alkaline non-lysosomal ceramidase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXV8, A0A1P8AZR2, A0A384KP75
      Conserved Domains (2) summary
      pfam04734
      Location:26 → 591
      Ceramidase_alk; Neutral/alkaline non-lysosomal ceramidase, N-terminal
      pfam17048
      Location:593 → 740
      Ceramidse_alk_C; Neutral/alkaline non-lysosomal ceramidase, C-terminal

    3. NM_129358.3 → NP_181337.2  Neutral/alkaline non-lysosomal ceramidase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181337.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IRY2, Q304B9, Q3EBK8, Q7XJQ9
      Conserved Domains (3) summary
      PTZ00487
      Location:26 → 738
      PTZ00487; ceramidase; Provisional
      pfam04734
      Location:26 → 591
      Ceramidase_alk; Neutral/alkaline non-lysosomal ceramidase, N-terminal
      pfam17048
      Location:593 → 740
      Ceramidse_alk_C; Neutral/alkaline non-lysosomal ceramidase, C-terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q304B9.1

    Gene LinkOut

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