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    GLY2 Metallo-hydrolase/oxidoreductase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820255, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GLY2
    Official Full Name
    Metallo-hydrolase/oxidoreductase superfamily protein
    Primary source
    TAIR:AT3G10850
    Locus tag
    AT3G10850
    See related
    Araport:AT3G10850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    GLX2-2; GLYOXALASE 2-2; GLYOXALASE II
    Summary
    glyoxalase II cytoplasmic isozyme (Glx2-2) mRNA, complete
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    Genomic context

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    See GLY2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (3397549..3399761, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Transcription elongation factor (TFIIS) family protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene Cytochrome b-c1 complex, subunit 8 protein Neighboring gene methyl esterase 17 Neighboring gene tropomyosin Neighboring gene Glycosyl hydrolase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The metal ion requirements of Arabidopsis thaliana Glx2-2 for catalytic activity. Limphong P, et al. J Biol Inorg Chem, 2010 Feb. PMID 19834746
    2. Molecular cloning and characterization of the thiolesterase glyoxalase II from Arabidopsis thaliana. Ridderström M, et al. Biochem J, 1997 Mar 1. PMID 9065762, Free PMC Article
    3. Molecular characterization of glyoxalase II from Arabidopsis thaliana. Maiti MK, et al. Plant Mol Biol, 1997 Nov. PMID 9349270
    4. Arabidopsis thaliana AHL family modulates hypocotyl growth redundantly by interacting with each other via the PPC/DUF296 domain. Zhao J, et al. Proc Natl Acad Sci U S A, 2013 Nov 26. PMID 24218605, Free PMC Article
    5. Identification and characterization of nuclear pore complex components in Arabidopsis thaliana. Tamura K, et al. Plant Cell, 2010 Dec. PMID 21189294, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_111922.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hydroxyacylglutathione hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hydroxyacylglutathione hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in secretory vesicle HDA PubMed 

    General protein information

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    Preferred Names
    Metallo-hydrolase/oxidoreductase superfamily protein
    NP_187696.1
    • GLY2; FUNCTIONS IN: hydroxyacylglutathione hydrolase activity; INVOLVED IN: methylglyoxal catabolic process to D-lactate; LOCATED IN: endomembrane system, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Beta-lactamase-like (InterPro:IPR001279), Hydroxyacylglutathione hydrolase (InterPro:IPR017782); BEST Arabidopsis thaliana protein match is: glyoxalase 2-4 (TAIR:AT1G06130.2); Has 13211 Blast hits to 13207 proteins in 2289 species: Archae - 256; Bacteria - 8297; Metazoa - 430; Fungi - 311; Plants - 206; Viruses - 0; Other Eukaryotes - 3711 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3397549..3399761 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111922.4 → NP_187696.1  Metallo-hydrolase/oxidoreductase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187696.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04844, O24496
      UniProtKB/TrEMBL
      A0A178VDR0, A0A5S9XB04, A0A654FGG9, Q0WQY6
      Conserved Domains (1) summary
      PLN02469
      Location:1 → 258
      PLN02469; hydroxyacylglutathione hydrolase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O24496.2

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