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    EXT-like hydroxyproline-rich glycoprotein family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828782, updated on 18-Sep-2024

    Summary

    Official Symbol
    EXT-like
    Official Full Name
    hydroxyproline-rich glycoprotein family protein
    Primary source
    TAIR:AT4G26750
    Locus tag
    AT4G26750
    See related
    Araport:AT4G26750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    extensin-like; F10M23.90; F10M23_90; homolog of mammalian LYST-INTERACTING PROTEIN5; LIP5
    Summary
    Encodes a protein involved in mediating plant responses to pathogenesis. Loss of function mutations have increased susceptibility to bacterial pathogens and are defective in pathogen induced endocytosis and vesicle trafficking. LIP5 physically interacts with SKD1 and that interaction is required for its resistance phenotype. LIP5 is phosphorylated by MPK3 and MPK6, both of which are components of the disease resistance pathway.
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    Genomic context

    See EXT-like in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (13475617..13478523, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene peroxygenase 1 Neighboring gene microtubule-associated protein 65-2 Neighboring gene Phosphatidate cytidylyltransferase family protein Neighboring gene Co-chaperone GrpE family protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_118809.5

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in cytoplasm PubMed 
    colocalizes_with endosome PubMed 
    located_in multivesicular body PubMed 
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    hydroxyproline-rich glycoprotein family protein
    NP_194405.1
    • hydroxyproline-rich glycoprotein family protein; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF605 (InterPro:IPR006745); BEST Arabidopsis thaliana protein match is: glucan synthase-like 11 (TAIR:AT3G59100.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13475617..13478523 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118809.5NP_194405.1  hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194405.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SZ15
      UniProtKB/TrEMBL
      A0A178UUB7, A0A5S9XW59, A0A654FT39
      Conserved Domains (2) summary
      PRK14086
      Location:248375
      dnaA; chromosomal replication initiator protein DnaA
      pfam04652
      Location:16142
      Vta1; Vta1 like
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