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    ROC5 rotamase cyclophilin 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829639, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ROC5
    Official Full Name
    rotamase cyclophilin 5
    Primary source
    TAIR:AT4G34870
    Locus tag
    AT4G34870
    See related
    Araport:AT4G34870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA CYCLOPHILIN 1; ATCYP1; CYCLOPHILIN; rotamase cyclophilin 5; ROTAMASE CYP
    Summary
    belongs to cyclophilin family
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    Genomic context

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    See ROC5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (16614204..16615313)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Phosphorylase superfamily protein Neighboring gene Chalcone and stilbene synthase family protein Neighboring gene Plant neutral invertase family protein Neighboring gene Amidase family protein Neighboring gene uncharacterized protein Neighboring gene xanthine dehydrogenase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Agrobacterium VirD2 protein interacts with plant host cyclophilins. Deng W, et al. Proc Natl Acad Sci U S A, 1998 Jun 9. PMID 9618535, Free PMC Article
    2. Characterization of the cyclophilin gene family of Arabidopsis thaliana and phylogenetic analysis of known cyclophilin proteins. Chou IT, et al. Plant Mol Biol, 1997 Dec. PMID 9426607
    3. Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID. Mair A, et al. Elife, 2019 Sep 19. PMID 31535972, Free PMC Article
    4. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
    5. Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study. Bindschedler LV, et al. Phytochemistry, 2008 Jul. PMID 18538804

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_119653.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in apoplast HDA PubMed 
    located_in chloroplast HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    rotamase cyclophilin 5
    NP_195213.1
    • rotamase cyclophilin 5 (ROC5); FUNCTIONS IN: peptidyl-prolyl cis-trans isomerase activity; INVOLVED IN: protein folding, signal transduction; LOCATED IN: cytosol, apoplast, chloroplast, plasma membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Cyclophilin-like (InterPro:IPR015891), Peptidyl-prolyl cis-trans isomerase, cyclophilin-type (InterPro:IPR002130), Peptidyl-prolyl cis-trans isomerase, cyclophilin-type, conserved site (InterPro:IPR020892); BEST Arabidopsis thaliana protein match is: rotamase CYP 3 (TAIR:AT2G16600.1); Has 16787 Blast hits to 16755 proteins in 2701 species: Archae - 108; Bacteria - 6977; Metazoa - 2940; Fungi - 1375; Plants - 1301; Viruses - 4; Other Eukaryotes - 4082 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      16614204..16615313
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119653.4 → NP_195213.1  rotamase cyclophilin 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195213.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WRR9, Q42406
      UniProtKB/TrEMBL
      A0A178UWH6, A0A5S9XZI5
      Conserved Domains (1) summary
      cd01926
      Location:4 → 169
      cyclophilin_ABH_like; Cyclophilin A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which accelerates protein folding ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q42406.1

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