U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    UBQ3 polyubiquitin 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831899, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    UBQ3
    Official Full Name
    polyubiquitin 3
    Primary source
    TAIR:AT5G03240
    Locus tag
    AT5G03240
    See related
    Araport:AT5G03240
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F15A17.270; F15A17_270; polyubiquitin 3; POLYUBIQUITIN 3 PROTEIN
    Summary
    encodes ubiquitin that is attached to proteins destined for degradation. UBQ3 is most homologous with UBQ4, and is expressed in higher levels in vegetative tissue but lower levels in flowers than UBQ4. UBQ3 encodes different number of ubiquitins in different ecotypes. UBQ3 transcript level is modulated by UV-B and light/dark treatments.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See UBQ3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (771660..773515, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Mediator complex, subunit Med7 Neighboring gene senescence regulator (Protein of unknown function, DUF584) Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene laccase 11 Neighboring gene lysine decarboxylase family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Gene regulation by low level UV-B radiation: identification by DNA array analysis. Brosché M, et al. Photochem Photobiol Sci, 2002 Sep. PMID 12665302
    2. Arabidopsis ubiquitin ligase MIEL1 mediates degradation of the transcription factor MYB30 weakening plant defence. Marino D, et al. Nat Commun, 2013. PMID 23403577
    3. Degradation of the stress-responsive enzyme formate dehydrogenase by the RING-type E3 ligase Keep on Going and the ubiquitin 26S proteasome system. McNeilly D, et al. Plant Mol Biol, 2018 Feb. PMID 29270890
    4. Arabidopsis ALIX is required for the endosomal localization of the deubiquitinating enzyme AMSH3. Kalinowska K, et al. Proc Natl Acad Sci U S A, 2015 Oct 6. PMID 26324913, Free PMC Article
    5. PUB22 and PUB23 U-BOX E3 ligases directly ubiquitinate RPN6, a 26S proteasome lid subunit, for subsequent degradation in Arabidopsis thaliana. Cho SK, et al. Biochem Biophys Res Commun, 2015 Sep 4. PMID 26188517

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001036747.1
    NM_120402.3
    NM_180698.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to UV-B IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure TAS
    Traceable Author Statement
    more info
    		  
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    polyubiquitin 3
    NP_001031824.1
    • polyubiquitin 3 (UBQ3); INVOLVED IN: protein modification process, response to UV-B, response to light stimulus, ubiquitin-dependent protein catabolic process; LOCATED IN: intracellular, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin subgroup (InterPro:IPR019956), Ubiquitin conserved site (InterPro:IPR019954), Ubiquitin (InterPro:IPR000626), Ubiquitin supergroup (InterPro:IPR019955); BEST Arabidopsis thaliana protein match is: ubiquitin 4 (TAIR:AT5G20620.1); Has 26684 Blast hits to 7218 proteins in 726 species: Archae - 0; Bacteria - 80; Metazoa - 12490; Fungi - 3021; Plants - 5505; Viruses - 651; Other Eukaryotes - 4937 (source: NCBI BLink).
    NP_568112.2
    • polyubiquitin 3 (UBQ3); INVOLVED IN: protein modification process, response to UV-B, response to light stimulus, ubiquitin-dependent protein catabolic process; LOCATED IN: intracellular, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin subgroup (InterPro:IPR019956), Ubiquitin conserved site (InterPro:IPR019954), Ubiquitin (InterPro:IPR000626), Ubiquitin supergroup (InterPro:IPR019955); BEST Arabidopsis thaliana protein match is: ubiquitin 4 (TAIR:AT5G20620.1); Has 26767 Blast hits to 7239 proteins in 727 species: Archae - 0; Bacteria - 104; Metazoa - 12533; Fungi - 3033; Plants - 5509; Viruses - 651; Other Eukaryotes - 4937 (source: NCBI BLink).
    NP_851029.1
    • polyubiquitin 3 (UBQ3); INVOLVED IN: protein modification process, response to UV-B, response to light stimulus, ubiquitin-dependent protein catabolic process; LOCATED IN: intracellular, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin subgroup (InterPro:IPR019956), Ubiquitin conserved site (InterPro:IPR019954), Ubiquitin (InterPro:IPR000626), Ubiquitin supergroup (InterPro:IPR019955); BEST Arabidopsis thaliana protein match is: ubiquitin 4 (TAIR:AT5G20620.1); Has 26684 Blast hits to 7218 proteins in 726 species: Archae - 0; Bacteria - 80; Metazoa - 12490; Fungi - 3021; Plants - 5505; Viruses - 651; Other Eukaryotes - 4937 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      771660..773515 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180698.3 → NP_851029.1  polyubiquitin 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851029.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1EC66
      UniProtKB/TrEMBL
      A0A1P8BGQ7, A0A5S9Y1S8, O49976
      Conserved Domains (1) summary
      cd01803
      Location:77 → 152
      Ubl_ubiquitin; ubiquitin-like (Ubl) domain found in ubiquitin

    2. NM_001036747.1 → NP_001031824.1  polyubiquitin 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031824.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1EC66
      UniProtKB/TrEMBL
      A0A1P8BGQ7, A0A5S9Y1S8, O49976
      Conserved Domains (1) summary
      cd01803
      Location:77 → 152
      Ubl_ubiquitin; ubiquitin-like (Ubl) domain found in ubiquitin

    3. NM_120402.3 → NP_568112.2  polyubiquitin 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568112.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1EC66
      UniProtKB/TrEMBL
      A0A1P8BGQ7, A0A5S9Y1S8, O49976
      Conserved Domains (1) summary
      cd01803
      Location:77 → 152
      Ubl_ubiquitin; ubiquitin-like (Ubl) domain found in ubiquitin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1EC66.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials