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    Transducin/WD40 repeat-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832409, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Transducin/WD40 repeat-like superfamily protein
    Primary source
    TAIR:AT5G23430
    Locus tag
    AT5G23430
    See related
    Araport:AT5G23430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K19M13.6; K19M13_6
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    19
    Sequence:
    Chromosome: 5; NC_003076.8 (7893594..7900563, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene high-mobility group box 6 Neighboring gene ncRNA Neighboring gene ferredoxin/thioredoxin reductase subunit A (variable subunit) 1 Neighboring gene long-chain base (LCB) kinase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis lue1 mutant defines a katanin p60 ortholog involved in hormonal control of microtubule orientation during cell growth. Bouquin T, et al. J Cell Sci, 2003 Mar 1. PMID 12571277
    2. KTN80 confers precision to microtubule severing by specific targeting of katanin complexes in plant cells. Wang C, et al. EMBO J, 2017 Dec 1. PMID 28978669, Free PMC Article
    3. Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. Lee JH, et al. Plant Cell, 2008 Jan. PMID 18223036, Free PMC Article
    4. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. Zhang Y, et al. Plant Cell, 2008 Jun. PMID 18552200, Free PMC Article
    5. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001343802.1
    NM_122250.2
    NM_180733.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cortical microtubule organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule severing IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in microtubule severing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of katanin complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of katanin complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Transducin/WD40 repeat-like superfamily protein
    NP_001318628.1
    • Transducin/WD40 repeat-like superfamily protein; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT5G08390.1); Has 113227 Blast hits to 41164 proteins in 1010 species: Archae - 84; Bacteria - 11989; Metazoa - 46351; Fungi - 25015; Plants - 14725; Viruses - 6; Other Eukaryotes - 15057 (source: NCBI BLink).
    NP_851064.1
    • Transducin/WD40 repeat-like superfamily protein; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT5G08390.1); Has 113433 Blast hits to 41213 proteins in 1020 species: Archae - 84; Bacteria - 12091; Metazoa - 46348; Fungi - 25039; Plants - 14792; Viruses - 6; Other Eukaryotes - 15073 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7893594..7900563 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180733.2 → NP_851064.1  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851064.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8H0T9, Q9FHL5
      UniProtKB/TrEMBL
      A0A178UEL9, A0A5S9Y732, A0A654G3M2
      Conserved Domains (3) summary
      cd00200
      Location:9 → 261
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:63 → 99
      7WD40; WD40 repeat [structural motif]
      pfam13925
      Location:678 → 829
      Katanin_con80; con80 domain of Katanin

    2. NM_001343802.1 → NP_001318628.1  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UEL9, A0A5S9Y732

    3. NM_122250.2 → NP_197734.2  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197734.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UEL9, A0A5S9Y732
      Conserved Domains (4) summary
      COG2319
      Location:8 → 261
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:9 → 261
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam13925
      Location:678 → 828
      Katanin_con80; con80 domain of Katanin
      sd00039
      Location:63 → 99
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H0T9.3

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