PDF1.2 plant defensin 1.2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: PDF1.2
Official Full Name: plant defensin 1.2
Primary source: TAIR:AT5G44420
Locus tag: AT5G44420
See related: Araport:AT5G44420
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: LCR77; LOW-MOLECULAR-WEIGHT CYSTEINE-RICH 77; MFC16.8; MFC16_8; PDF1.2A; plant defensin 1.2; PLANT DEFENSIN 1.2A
Summary: Encodes an ethylene- and jasmonate-responsive plant defensin. mRNA levels are not responsive to salicylic acid treatment; although jasmonate and salicylic acid can act synergistically to enhance the expression of this gene. Belongs to the plant defensin (PDF) family with the following members: At1g75830/PDF1.1, At5g44420/PDF1.2a, At2g26020/PDF1.2b, At5g44430/PDF1.2c, At2g26010/PDF1.3, At1g19610/PDF1.4, At1g55010/PDF1.5, At2g02120/PDF2.1, At2g02100/PDF2.2, At2g02130/PDF2.3, At1g61070/PDF2.4, At5g63660/PDF2.5, At2g02140/PDF2.6, At5g38330/PDF3.1 and At4g30070/PDF3.2.
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Genomic context

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See PDF1.2 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 2

Sequence:: Chromosome: 5; NC_003076.8 (17906968..17907638, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

the opposing function of two transcription factors, ethylene insensitive3 (EIN3) and EIN3-Like1 (EIL1), in salicylic acid-mediated suppression and jasmonic acid-mediated activation of PLANT DEFENSIN1.2 (PDF1.2), through ORA59.
Title: ORA59 and EIN3 interaction couples jasmonate-ethylene synergistic action to antagonistic salicylic acid regulation of PDF expression.
Resistance induced by Paenibacillus alvei K165 depends on salicylate and jasmonate-dependent defense pathways, as evidenced by an increased transient accumulation of PR1 and PDF1.2 transcripts in the aerial parts of infected plants treated with K165.
Title: The Innate Immune Signaling System as a Regulator of Disease Resistance and Induced Systemic Resistance Activity Against Verticillium dahliae.
Dtta indicate that the expression of marker genes PR1 and BGL2 for the salicylic acid (SA) and the PDF1.2 for the jasmonic acid-ethylene (JA-ET) signalling pathways was enhanced in 10 muM Cd-treated non-infected plants.
Title: Signal cross talk in Arabidopsis exposed to cadmium, silicon, and Botrytis cinerea.
Natural variation in jasmonic acid-induced PDF1.2 expression is associated with basal resistance against the nectrophic fungus Plectosphaerella cucumerina.
Title: Genetic dissection of basal defence responsiveness in accessions of Arabidopsis thaliana.
ORA59 and two functionally equivalent GCC box binding sites form the module that enables the PDF1.2 gene to respond synergistically to simultaneous activation of the jasmonate and ethylene signaling pathways
Title: Two GCC boxes and AP2/ERF-domain transcription factor ORA59 in jasmonate/ethylene-mediated activation of the PDF1.2 promoter in Arabidopsis.
Growth and infection of Phakopsora pachyrhizi hyphae in Arabidopsis were terminated at the mesophyll boundary, and associated with expression of PDF1.2.
Title: Characterization of nonhost resistance of Arabidopsis to the Asian soybean rust.
Mmutations of WRKY33 gene encoding a WRKY transcription factor cause enhanced susceptibility to Botrytis cinerea and Alternaria brassicicola concomitant with reduced expression of the jasmonate-regulated plant defensin PDF1.2 gene.
Title: Arabidopsis WRKY33 transcription factor is required for resistance to necrotrophic fungal pathogens.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_123809.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within defense response	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within jasmonic acid and ethylene-dependent systemic resistance	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within response to ethylene	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to insect	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to jasmonic acid	IEP Inferred from Expression Pattern more info	PubMed
NOT involved_in response to salicylic acid	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: plant defensin 1.2

NP_199255.1

plant defensin 1.2 (PDF1.2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: response to ethylene stimulus, response to jasmonic acid stimulus, jasmonic acid and ethylene-dependent systemic resistance, defense response, response to insect; LOCATED IN: endomembrane system, cell wall; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Gamma thionin (InterPro:IPR008176), Knottin (InterPro:IPR003614); BEST Arabidopsis thaliana protein match is: plant defensin 1.2b (TAIR:AT2G26020.1); Has 182 Blast hits to 182 proteins in 41 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 181; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).