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    HSP81-2 heat shock protein 81-2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835701, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HSP81-2
    Official Full Name
    heat shock protein 81-2
    Primary source
    TAIR:AT5G56030
    Locus tag
    AT5G56030
    See related
    Araport:AT5G56030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtHsp90.2; EARLY-RESPONSIVE TO DEHYDRATION 8; ERD8; HEAT SHOCK PROTEIN 90.2; heat shock protein 81-2; HEAT SHOCK PROTEIN 81-2; heat shock protein 81.2; HEAT SHOCK PROTEIN 90.2; HSP81.2; HSP90.2; MDA7.7; MDA7_7
    Summary
    A member of heat shock protein 90 (HSP90) gene family. Expressed in all tissues and abundant in root apical meristem, pollen and tapetum. Expression is NOT heat-induced but induced by IAA and NaCl. Interacts with HsfA1d in the cytosol and the nucleus and negatively regulates HsfA1d. Did not bind to AtHsfA4c.
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    Genomic context

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    See HSP81-2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (22686473..22689671)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene heat shock protein 81-3 Neighboring gene Got1/Sft2-like vescicle transport protein family Neighboring gene Leucine-rich receptor-like protein kinase family protein Neighboring gene late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spatiotemporal expression patterns of cytosolic AtHSP90-2 in Arabidopsis seedlings. Kozeko L, et al. Plant Signal Behav, 2023 Dec 31. PMID 37071581, Free PMC Article
    2. HSP90 Contributes to Entrainment of the Arabidopsis Circadian Clock via the Morning Loop. Davis AM, et al. Genetics, 2018 Dec. PMID 30337341, Free PMC Article
    3. Cytosolic HSP90 regulates the heat shock response that is responsible for heat acclimation in Arabidopsis thaliana. Yamada K, et al. J Biol Chem, 2007 Dec 28. PMID 17965410
    4. Tight regulation of expression of two Arabidopsis cytosolic Hsp90 genes during embryo development. Prasinos C, et al. J Exp Bot, 2005 Feb. PMID 15582930
    5. Isolation and analysis of the expression of two genes for the 81-kilodalton heat-shock proteins from Arabidopsis. Takahashi T, et al. Plant Physiol, 1992 Jun. PMID 16668895, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Spatiotemporal expression patterns of cytosolic AtHSP90-2 in Arabidopsis seedlings.
      Title: Spatiotemporal expression patterns of cytosolic AtHSP90-2 in Arabidopsis seedlings.
    2. we define a potential pathway for how HSP90.2 can entrain the Arabidopsis circadian oscillator.
      Title: HSP90 Contributes to Entrainment of the Arabidopsis Circadian Clock via the Morning Loop.
    3. Results show that the induction expression of ABA-responsive genes under salt and drought stress was delayed by constitutive overexpression of cytosolic AtHsp90.2, but was hardly affected by that of organellar AtHsp90.5 and AtHsp90.7.
      Title: Overexpression of AtHsp90.2, AtHsp90.5 and AtHsp90.7 in Arabidopsis thaliana enhances plant sensitivity to salt and drought stresses.
    4. Nuclear magnetic resonance spectroscopy and mutational analysis of HSP90 revealed the nature of its binding with the CS domain of SGT1 which is required for innate immunity in plants and animals. [HSP90]
      Title: Structural and functional analysis of SGT1-HSP90 core complex required for innate immunity in plants.
    5. HSP90.2 is involved in the heat shock response in A. thaliana. It interacts with AtHsfA7a and AtHsfB1 but only weakly interacts or does not interact with AtHsfA4c.
      Title: Cytosolic HSP90 regulates the heat shock response that is responsible for heat acclimation in Arabidopsis thaliana.
    6. The regulation of AtHSP90-1 and AtHSP90-3 proteins during seed development in A. thaliana. [HSP90-3]
      Title: Tight regulation of expression of two Arabidopsis cytosolic Hsp90 genes during embryo development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203624.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding HDA PubMed 
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chaperone-mediated protein complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in chaperone-mediated protein folding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within heat acclimation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein stabilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within stomatal closure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in plant-type cell wall HDA PubMed 
    located_in plasmodesma HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    heat shock protein 81-2
    NP_001190553.1
    • heat shock protein 81-2 (HSP81-2); CONTAINS InterPro DOMAIN/s: Chaperone protein htpG (InterPro:IPR001404), Heat shock protein Hsp90, conserved site (InterPro:IPR019805), Heat shock protein Hsp90, C-terminal (InterPro:IPR020576), Heat shock protein Hsp90, N-terminal (InterPro:IPR020575), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), ATPase-like, ATP-binding domain (InterPro:IPR003594); BEST Arabidopsis thaliana protein match is: HEAT SHOCK PROTEIN 81.4 (TAIR:AT5G56000.1).
    NP_200414.1
    • heat shock protein 81-2 (HSP81-2); FUNCTIONS IN: protein binding, ATP binding; INVOLVED IN: in 9 processes; LOCATED IN: cytosol, mitochondrion, cell wall, nucleus; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Chaperone protein htpG (InterPro:IPR001404), Heat shock protein Hsp90, conserved site (InterPro:IPR019805), Heat shock protein Hsp90, C-terminal (InterPro:IPR020576), Heat shock protein Hsp90, N-terminal (InterPro:IPR020575), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), ATPase-like, ATP-binding domain (InterPro:IPR003594); BEST Arabidopsis thaliana protein match is: heat shock protein 81-3 (TAIR:AT5G56010.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22686473..22689671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124985.5 → NP_200414.1  heat shock protein 81-2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200414.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P55737, Q8H158
      UniProtKB/TrEMBL
      A0A178ULZ9, A0A5S9YGS6
      Conserved Domains (3) summary
      PTZ00272
      Location:5 → 699
      PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional
      pfam00183
      Location:184 → 699
      HSP90; Hsp90 protein
      pfam02518
      Location:32 → 181
      HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase

    2. NM_001203624.1 → NP_001190553.1  heat shock protein 81-2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190553.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178ULZ9, A0A5S9YGS6, F4K6B6
      Conserved Domains (3) summary
      PTZ00272
      Location:5 → 728
      PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional
      pfam00183
      Location:213 → 728
      HSP90; Hsp90 protein
      pfam02518
      Location:94 → 210
      HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P55737.1

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