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    TUA6 Tubulin/FtsZ family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827154, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TUA6
    Official Full Name
    Tubulin/FtsZ family protein
    Primary source
    TAIR:AT4G14960
    Locus tag
    AT4G14960
    See related
    Araport:AT4G14960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Tubulin alpha-6
    Summary
    Encodes an alpha-tubulin isoform required for right handed helical growth.
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    Genomic context

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    See TUA6 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (8548417..8550495, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Survival protein SurE-like phosphatase/nucleotidase Neighboring gene amine oxidase 1 Neighboring gene SNARE associated Golgi protein family Neighboring gene membrane-associated progesterone binding protein 4 Neighboring gene fanconi anemia group D2 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GFP-tagging of cell components reveals the dynamics of subcellular re-organization in response to infection of Arabidopsis by oomycete pathogens. Takemoto D, et al. Plant J, 2003 Feb. PMID 12609049
    2. Altered microtubule dynamics by expression of modified alpha-tubulin protein causes right-handed helical growth in transgenic Arabidopsis plants. Abe T, et al. Plant J, 2005 Jul. PMID 15998306
    3. Growth stimulation in inflorescences of an Arabidopsis tubulin mutant under microgravity conditions in space. Hoson T, et al. Plant Biol (Stuttg), 2014 Jan. PMID 24148142
    4. An Arabidopsis thaliana tubulin mutant with conditional root-skewing phenotype. Ishida T, et al. J Plant Res, 2007 Sep. PMID 17641820
    5. Arabidopsis tubulin folding cofactor B interacts with alpha-tubulin in vivo. Dhonukshe P, et al. Plant Cell Physiol, 2006 Oct. PMID 16928693

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The degree of growth stimulation tended to be higher in the tua6 mutant than the wild-type Columbia.
      Title: Growth stimulation in inflorescences of an Arabidopsis tubulin mutant under microgravity conditions in space.
    2. Cys213Tyr mutant roots twist in a right-handed direction and have shallow left-handed cortical microtubule arrays when challenged with low doses of microtubule drugs.
      Title: An Arabidopsis thaliana tubulin mutant with conditional root-skewing phenotype.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_117582.4
    NM_179057.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to gravity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 
    part_of tubulin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    Tubulin/FtsZ family protein
    NP_193232.1
    • TUA6; FUNCTIONS IN: protein binding, structural constituent of cytoskeleton; INVOLVED IN: response to salt stress, microtubule cytoskeleton organization, cellular response to gravity; LOCATED IN: in 8 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Alpha tubulin (InterPro:IPR002452), Tubulin (InterPro:IPR000217), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin, conserved site (InterPro:IPR017975), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: tubulin alpha-2 chain (TAIR:AT1G50010.1); Has 22664 Blast hits to 22566 proteins in 4681 species: Archae - 4; Bacteria - 25; Metazoa - 4398; Fungi - 13427; Plants - 1532; Viruses - 0; Other Eukaryotes - 3278 (source: NCBI BLink).
    NP_849388.1
    • TUA6; FUNCTIONS IN: protein binding, structural constituent of cytoskeleton; INVOLVED IN: response to salt stress, microtubule cytoskeleton organization, cellular response to gravity; LOCATED IN: in 8 components; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Alpha tubulin (InterPro:IPR002452), Tubulin (InterPro:IPR000217), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin, conserved site (InterPro:IPR017975), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: tubulin alpha-2 chain (TAIR:AT1G50010.1); Has 22344 Blast hits to 22275 proteins in 4636 species: Archae - 4; Bacteria - 22; Metazoa - 4264; Fungi - 13337; Plants - 1462; Viruses - 0; Other Eukaryotes - 3255 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      8548417..8550495 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117582.4 → NP_193232.1  Tubulin/FtsZ family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193232.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P29511
      UniProtKB/TrEMBL
      A0A178UXP7, A0A5S9XT55, Q944I2
      Conserved Domains (1) summary
      PLN00221
      Location:1 → 450
      PLN00221; tubulin alpha chain; Provisional

    2. NM_179057.1 → NP_849388.1  Tubulin/FtsZ family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849388.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B9DFF8, Q944I2
      Conserved Domains (2) summary
      PLN00221
      Location:1 → 426
      PLN00221; tubulin alpha chain; Provisional
      cd02186
      Location:2 → 386
      alpha_tubulin; The alpha-tubulin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P29511.1

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