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    U2 snRNP auxilliary factor, large subunit, splicing factor [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842382, updated on 18-Sep-2024

    Summary

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    Official Full Name
    U2 snRNP auxilliary factor, large subunit, splicing factor
    Primary source
    TAIR:AT1G60900
    Locus tag
    AT1G60900
    See related
    Araport:AT1G60900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T7P1.5; T7P1_5
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    13
    Sequence:
    Chromosome: 1; NC_003070.9 (22423894..22428053)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Phosphatidylinositol-4-phosphate 5-kinase family protein Neighboring gene AGAMOUS-like-56 Neighboring gene tRNA-Gly Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtU2AF65b functions in abscisic acid mediated flowering via regulating the precursor messenger RNA splicing of ABI5 and FLC in Arabidopsis. Xiong F, et al. New Phytol, 2019 Jul. PMID 30790290
    2. A homolog of splicing factor SF1 is essential for development and is involved in the alternative splicing of pre-mRNA in Arabidopsis thaliana. Jang YH, et al. Plant J, 2014 May. PMID 24580679
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Abscissic acid (ABA)-responsive AtU2AF65b functions in the pre-mRNA splicing of FLC and ABI5 in shoot apex, whereby AtU2AF65b is involved in ABA-mediated flowering transition in Arabidopsis. [AtU2AF65b]
      Title: AtU2AF65b functions in abscisic acid mediated flowering via regulating the precursor messenger RNA splicing of ABI5 and FLC in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_104771.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    U2 snRNP auxilliary factor, large subunit, splicing factor
    NP_176287.3
    • U2 snRNP auxilliary factor, large subunit, splicing factor; FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: mRNA processing; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677), U2 snRNP auxilliary factor, large subunit, splicing factor (InterPro:IPR006529); BEST Arabidopsis thaliana protein match is: U2 snRNP auxilliary factor, large subunit, splicing factor (TAIR:AT4G36690.4); Has 95343 Blast hits to 42389 proteins in 1915 species: Archae - 82; Bacteria - 12197; Metazoa - 47091; Fungi - 9469; Plants - 8106; Viruses - 663; Other Eukaryotes - 17735 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      22423894..22428053
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104771.4 → NP_176287.3  U2 snRNP auxilliary factor, large subunit, splicing factor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176287.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L716, Q9C961
      UniProtKB/TrEMBL
      A0A178WAX1, A0A654EJT8
      Conserved Domains (1) summary
      TIGR01642
      Location:190 → 587
      U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L716.2

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