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    ztf-17 Zinc finger transcription factor family protein 17 [ Caenorhabditis elegans ]

    Gene ID: 174269, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ztf-17
    Official Full Name
    Zinc finger transcription factor family protein 17
    Primary source
    WormBase:WBGene00011639
    Locus tag
    CELE_T09A5.12
    See related
    AllianceGenome:WB:WBGene00011639
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be part of PcG protein complex and transcription regulator complex. Is expressed in body wall musculature; gonad; intestine; pharynx; and ventral nerve cord. Orthologous to human ZFP42 (ZFP42 zinc finger protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ztf-17 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    13
    Sequence:
    Chromosome: II; NC_003280.10 (7866256..7870162, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Spindle apparatus protein lin-5 Neighboring gene Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Neighboring gene MFS domain-containing protein Neighboring gene Peroxin/Ferlin domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6. Liu WJ, et al. BMC Dev Biol, 2014 May 13. PMID 24885717, Free PMC Article
    2. KIN-4/MAST kinase promotes PTEN-mediated longevity of Caenorhabditis elegans via binding through a PDZ domain. An SWA, et al. Aging Cell, 2019 Jun. PMID 30773781, Free PMC Article
    3. An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. Meissner B, et al. PLoS Genet, 2009 Jun. PMID 19557190, Free PMC Article
    4. Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. Gottschalk A, et al. EMBO J, 2005 Jul 20. PMID 15990870, Free PMC Article
    5. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of PcG protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Zinc finger transcription factor family protein 17
    NP_495656.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7866256..7870162 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063255.8 → NP_495656.2  Zinc finger transcription factor family protein 17 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495656.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P45972
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P45972.3

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