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    slc-17.7 Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179308, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc-17.7
    Official Full Name
    Major facilitator superfamily (MFS) profile domain-containing protein
    Primary source
    WormBase:WBGene00022788
    Locus tag
    CELE_ZK682.2
    See related
    AllianceGenome:WB:WBGene00022788
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See slc-17.7 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (9263800..9266499, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class H Neighboring gene Nuclear hormone receptor E75 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Helix-loop-helix protein 10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Neuronally produced betaine acts via a ligand-gated ion channel to control behavioral states. Hardege I, et al. Proc Natl Acad Sci U S A, 2022 Nov 29. PMID 36413500, Free PMC Article
    2. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Major facilitator superfamily (MFS) profile domain-containing protein
    NP_505399.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9263800..9266499 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072998.5 → NP_505399.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505399.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23576
      Conserved Domains (1) summary
      cl28910
      Location:31 → 467
      MFS; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version

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