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    cdr-3 CaDmium Responsive [ Caenorhabditis elegans ]

    Gene ID: 183780, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cdr-3
    Official Full Name
    CaDmium Responsive
    Primary source
    WormBase:WBGene00008297
    Locus tag
    CELE_C54D10.2
    See related
    AllianceGenome:WB:WBGene00008297
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in stress response to cadmium ion. Predicted to be located in membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cdr-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (12416358..12417377, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene CaDmium Responsive Neighboring gene CaDmium Responsive Neighboring gene ShKT domain-containing protein Neighboring gene RDS/peripherin-like protein xRDS35 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of a family of Caenorhabditis elegans genes that is homologous to the cadmium-responsive gene cdr-1. Dong J, et al. Biochim Biophys Acta, 2005 Jan 21. PMID 15652154
    2. Molecular strategies of the Caenorhabditis elegans dauer larva to survive extreme desiccation. Erkut C, et al. PLoS One, 2013. PMID 24324795, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in stress response to cadmium ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CaDmium Responsive
    NP_506115.2
    • Product from WormBase gene class cdr;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12416358..12417377 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073714.2 → NP_506115.2  CaDmium Responsive [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506115.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18832, Q5XXC0
      Conserved Domains (2) summary
      cd03193
      Location:200 → 268
      GST_C_Metaxin; C-terminal, alpha helical domain of Metaxin and related proteins
      cd03080
      Location:46 → 117
      GST_N_Metaxin_like; GST_N family, Metaxin subfamily, Metaxin-like proteins; a heterogenous group of proteins, predominantly uncharacterized, with similarity to metaxins and GSTs. Metaxin 1 is a component of a preprotein import complex of the mitochondrial outer membrane. It ...
    Nucleotide Protein
    Heading Accession and Version

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