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    kvs-3 BTB domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 185719, updated on 9-Dec-2024

    Summary

    Official Symbol
    kvs-3
    Official Full Name
    BTB domain-containing protein
    Primary source
    WormBase:WBGene00018402
    Locus tag
    CELE_F44A2.2
    See related
    AllianceGenome:WB:WBGene00018402
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable potassium channel regulator activity. Involved in long-term memory. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in membrane. Is expressed in nervous system. Orthologous to several human genes including KCNF1 (potassium voltage-gated channel modifier subfamily F member 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See kvs-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (9318311..9321347)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Ala Neighboring gene N-acetyltransferase domain-containing protein Neighboring gene NOT2/NOT3/NOT5 C-terminal domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables potassium channel regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables voltage-gated potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in action potential IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in long-term memory IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in potassium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of monoatomic ion channel complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of voltage-gated potassium channel complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of voltage-gated potassium channel complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    BTB domain-containing protein
    NP_505407.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9318311..9321347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073006.5NP_505407.2  BTB domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505407.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20381
      Conserved Domains (4) summary
      smart00225
      Location:26133
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00520
      Location:206407
      Ion_trans; Ion transport protein
      pfam02214
      Location:28127
      BTB_2; BTB/POZ domain
      pfam07885
      Location:324405
      Ion_trans_2; Ion channel