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    ulp-5 Ubiquitin-like protease family profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186900, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ulp-5
    Official Full Name
    Ubiquitin-like protease family profile domain-containing protein
    Primary source
    WormBase:WBGene00006740
    Locus tag
    CELE_K02F2.4
    See related
    AllianceGenome:WB:WBGene00006740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable deSUMOylase activity. Predicted to be involved in protein desumoylation. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ulp-5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (6812660..6814249)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase Neighboring gene Conserved secreted protein Neighboring gene ncRNA Neighboring gene Splicing factor 3B subunit 3 Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Erratum: Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans. Pelisch F, et al. Nat Commun, 2015 Feb 12. PMID 25672768, Free PMC Article
    2. Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans. Pelisch F, et al. Nat Commun, 2014 Dec 5. PMID 25475837, Free PMC Article
    3. A genome-wide RNAi screen identifies factors required for distinct stages of C. elegans piRNA biogenesis. Goh WS, et al. Genes Dev, 2014 Apr 1. PMID 24696458, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ulp-5 is required for the biogenesis of 21U-RNAs and is likely involved in the transcription of capped pre-21U precursor RNAs.
      Title: A genome-wide RNAi screen identifies factors required for distinct stages of C. elegans piRNA biogenesis.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables deSUMOylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein desumoylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Ubiquitin-like protease family profile domain-containing protein
    NP_491952.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6812660..6814249
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059551.3 → NP_491952.1  Ubiquitin-like protease family profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491952.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44984
      Conserved Domains (1) summary
      pfam02902
      Location:50 → 302
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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