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    egli-1 Transmembrane protein 41 homolog [ Caenorhabditis elegans ]

    Gene ID: 183942, updated on 9-Dec-2024

    Summary

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    Official Symbol
    egli-1
    Official Full Name
    Transmembrane protein 41 homolog
    Primary source
    WormBase:WBGene00006520
    Locus tag
    CELE_D2013.10
    See related
    AllianceGenome:WB:WBGene00006520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in autophagosome assembly. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including body wall musculature; intestine; nervous system; pharynx; and reproductive system. Orthologous to human TMEM41B (transmembrane protein 41B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See egli-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003280.10 (9323960..9324700)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene WD repeat and FYVE domain-containing protein 2 Neighboring gene ncRNA Neighboring gene Ras-related protein rab-39 Neighboring gene Dynamin-like GTPase OPA1, mitochondrial Neighboring gene GRAM domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Loss of egli-1, the Caenorhabditis elegans Orthologue of a Downstream Target of SMN, Leads to Abnormalities in Sensorimotor Integration. Da Silva JD, et al. Mol Neurobiol, 2020 Mar. PMID 31797327
    2. Mos1 mutagenesis reveals a diversity of mechanisms affecting response of Caenorhabditis elegans to the bacterial pathogen Microbacterium nematophilum. Yook K, et al. Genetics, 2007 Feb. PMID 17151260, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane protein 41 homolog
    NP_495985.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9323960..9324700
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063584.3 → NP_495985.1  Transmembrane protein 41 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495985.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O62126
      Conserved Domains (1) summary
      pfam09335
      Location:86 → 206
      SNARE_assoc; SNARE associated Golgi protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O62126.1

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