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    lron-2 Leucine-rich repeat-containing protein 15-like [ Caenorhabditis elegans ]

    Gene ID: 179309, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lron-2
    Official Full Name
    Leucine-rich repeat-containing protein 15-like
    Primary source
    WormBase:WBGene00022789
    Locus tag
    CELE_ZK682.5
    See related
    AllianceGenome:WB:WBGene00022789
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in cell development. Predicted to be located in membrane. Is expressed in pharynx and tail. Orthologous to human LRRC15 (leucine rich repeat containing 15). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lron-2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    10
    Sequence:
    Chromosome: V; NC_003283.11 (9284124..9287560, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Helix-loop-helix protein 10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cell development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Leucine-rich repeat-containing protein 15-like
    NP_505402.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9284124..9287560 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073001.7 → NP_505402.1  Leucine-rich repeat-containing protein 15-like [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505402.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23580
      Conserved Domains (4) summary
      cd00116
      Location:109 → 294
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:110 → 133
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:86 → 144
      LRR_8; Leucine rich repeat
      pfam14798
      Location:481 → 504
      Ca_hom_mod; Calcium homeostasis modulator
    Nucleotide Protein
    Heading Accession and Version

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