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    gcsh-1 Glycine cleavage system H protein [ Caenorhabditis elegans ]

    Gene ID: 183902, updated on 9-Dec-2024

    Summary

    Official Symbol
    gcsh-1
    Official Full Name
    Glycine cleavage system H protein
    Primary source
    WormBase:WBGene00008354
    Locus tag
    CELE_D1025.2
    See related
    AllianceGenome:WB:WBGene00008354
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in glycine decarboxylation via glycine cleavage system. Predicted to be part of glycine cleavage complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome. Orthologous to human GCSH (glycine cleavage system protein H). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See gcsh-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    3
    Sequence:
    Chromosome: X; NC_003284.9 (14514130..14515073, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DUF38 domain-containing protein Neighboring gene SCD domain-containing protein Neighboring gene ERCC4 domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in glycine decarboxylation via glycine cleavage system IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glycine decarboxylation via glycine cleavage system IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of glycine cleavage complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of glycine cleavage complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Glycine cleavage system H protein
    NP_510414.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      14514130..14515073 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078013.7NP_510414.1  Glycine cleavage system H protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510414.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62122
      Conserved Domains (1) summary
      pfam01597
      Location:24144
      GCV_H; Glycine cleavage H-protein