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    bus-2 Hexosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 176977, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bus-2
    Official Full Name
    Hexosyltransferase
    Primary source
    WormBase:WBGene00044618
    Locus tag
    CELE_K08D12.5
    See related
    AllianceGenome:WB:WBGene00044618
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable glycosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. Is expressed in head muscle; intestine; seam cell; and spermatheca. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See bus-2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (1699899..1702856)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene C6 domain-containing protein Neighboring gene Proteasome subunit beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans bus-2 mutant reveals a new class of O-glycans affecting bacterial resistance. Palaima E, et al. J Biol Chem, 2010 Jun 4. PMID 20385555, Free PMC Article
    2. Independent synchronized control and visualization of interactions between living cells and organisms. Rouger V, et al. Biophys J, 2014 May 20. PMID 24853738, Free PMC Article
    3. The hmsHFRS operon of Xenorhabdus nematophila is required for biofilm attachment to Caenorhabditis elegans. Drace K, et al. Appl Environ Microbiol, 2008 Jul. PMID 18515487, Free PMC Article
    4. Mos1 mutagenesis reveals a diversity of mechanisms affecting response of Caenorhabditis elegans to the bacterial pathogen Microbacterium nematophilum. Yook K, et al. Genetics, 2007 Feb. PMID 17151260, Free PMC Article
    5. Glycosylation genes expressed in seam cells determine complex surface properties and bacterial adhesion to the cuticle of Caenorhabditis elegans. Gravato-Nobre MJ, et al. Genetics, 2011 Jan. PMID 20980242, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Hexosyltransferase
    NP_001255233.1
    • Confirmed by transcript evidence
    NP_001255234.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      1699899..1702856
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268304.4 → NP_001255233.1  Hexosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255233.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D6QX34, H2L0F4
      Conserved Domains (1) summary
      cl21608
      Location:81 → 269
      Galactosyl_T; Galactosyltransferase

    2. NM_001268305.5 → NP_001255234.1  Hexosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255234.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3KZG1, D6QX34
      Conserved Domains (1) summary
      cl21608
      Location:75 → 263
      Galactosyl_T; Galactosyltransferase
    Nucleotide Protein
    Heading Accession and Version

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