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    tag-153 NOT2/NOT3/NOT5 C-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179312, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tag-153
    Official Full Name
    NOT2/NOT3/NOT5 C-terminal domain-containing protein
    Primary source
    WormBase:WBGene00006499
    Locus tag
    CELE_F44A2.1
    See related
    AllianceGenome:WB:WBGene00006499
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening and regulation of stem cell population maintenance. Predicted to be part of CCR4-NOT core complex. Predicted to be active in P-body. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tag-153 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    14
    Sequence:
    Chromosome: V; NC_003283.11 (9323085..9327213)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene BTB domain-containing protein Neighboring gene N-acetyltransferase domain-containing protein Neighboring gene Phospholipid/glycerol acyltransferase domain-containing protein Neighboring gene Acyltransferase Neighboring gene UnCoupling Protein (mitochondrial substrate carrier)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Caenorhabditis elegans fibroblast growth factor receptor signaling can occur independently of the multi-substrate adaptor FRS2. Lo TW, et al. Genetics, 2010 Jun. PMID 20308281, Free PMC Article
    2. COP9 signalosome component CSN-5 stabilizes PUF proteins FBF-1 and FBF-2 in Caenorhabditis elegans germline stem and progenitor cells. Osterli E, et al. Genetics, 2024 May 7. PMID 38427913,
    3. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Tsukamoto T, et al. Genetics, 2017 Aug. PMID 28576864, Free PMC Article
    4. ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1. Wang W, et al. Traffic, 2008 May. PMID 18298590, Free PMC Article
    5. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA poly(A) tail shortening IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of stem cell population maintenance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of stem cell population maintenance IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of CCR4-NOT core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of CCR4-NOT core complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NOT2/NOT3/NOT5 C-terminal domain-containing protein
    NP_505409.1
    • Confirmed by transcript evidence
    NP_505410.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9323085..9327213
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073008.7 → NP_505409.1  NOT2/NOT3/NOT5 C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505409.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L031
      Conserved Domains (1) summary
      cl02384
      Location:439 → 532
      NOT2_3_5; NOT2 / NOT3 / NOT5 family

    2. NM_073009.6 → NP_505410.1  NOT2/NOT3/NOT5 C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505410.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q27420
      Conserved Domains (1) summary
      cl02384
      Location:203 → 291
      NOT2_3_5; NOT2 / NOT3 / NOT5 family
    Nucleotide Protein
    Heading Accession and Version

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